Study of the characteristics of a scintillation array and single pixels for nuclear medicine imaging applications

Ma, Hongguang; Ma, Wei; Zeng, Hui; Wang, Zhaomin; Xu, Zizong

doi:10.1088/1674-1137/33/4/009

Cited by 3 publications

(2 citation statements)

References 9 publications

(9 reference statements)

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“…This detector exhibited 64.41% efficiency at a photon energy of 140 keV (figure 3). The intrinsic resolution of the 5-mm thick NaI(Tl) detector was 2.3 mm [36].…”

Section: Configuration Of Small Animal Spect Systemsmentioning

confidence: 99%

Feasibility of a CdTe-based SPECT for high-resolution low-dose small animal imaging: a Monte Carlo simulation study

Park¹,

Yu²,

Lee³

et al. 2014

J. Inst.

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Dedicated single-photon-emission computed tomography (SPECT) systems based on pixelated semiconductors such as cadmium telluride (CdTe) are in development to study small animal models of human disease. In an effort to develop a high-resolution, low-dose system for small animal imaging, we compared a CdTe-based SPECT system and a conventional NaI(Tl)based SPECT system in terms of spatial resolution, sensitivity, contrast, and contrast-to-noise ratio (CNR). In addition, we investigated the radiation absorbed dose and calculated a figure of merit (FOM) for both SPECT systems. Using the conventional NaI(Tl)-based SPECT system, we achieved a spatial resolution of 1.66 mm at a 30 mm source-to-collimator distance, and a resolution of 2.4-mm hot-rods. Using the newly-developed CdTe-based SPECT system, we achieved a spatial resolution of 1.32 mm FWHM at a 30 mm source-to-collimator distance, and a resolution of 1.7-mm hot-rods. The sensitivities at a 30 mm source-to-collimator distance were 115.73 counts/sec/MBq and 83.38 counts/sec/MBq for the CdTe-based SPECT and conventional NaI(Tl)-based SPECT systems, respectively. To compare quantitative measurements in the mouse brain, we calculated the CNR for images from both systems. The CNR from the CdTe-based SPECT system was 4.41, while that from the conventional NaI(Tl)-based SPECT system was 3.11 when the injected striatal dose was 160 Bq/voxel. The CNR increased as a function of injected dose in both systems. The FOM of the CdTe-based SPECT system was superior to that of the conventional NaI(Tl)-based SPECT system, and the highest FOM was achieved with the CdTe-based SPECT at a dose of 40 Bq/voxel injected into the striatum. Thus, a CdTe-based SPECT system showed significant improvement in performance compared with a conventional system in terms

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“…This detector exhibited 64.41% efficiency at a photon energy of 140 keV (figure 3). The intrinsic resolution of the 5-mm thick NaI(Tl) detector was 2.3 mm [36].…”

Section: Configuration Of Small Animal Spect Systemsmentioning

confidence: 99%

Feasibility of a CdTe-based SPECT for high-resolution low-dose small animal imaging: a Monte Carlo simulation study

Park¹,

Yu²,

Lee³

et al. 2014

J. Inst.

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“…There are many clinical treatments for AO, but the principle is basically the same, that is, to reduce or completely clear the axillary ASG, reduce the secretion of unsaturated branched fatty acids to reduce or eliminate the special smell of axilla [2]. At present, the main methods of treatment for AO include surgical treatment and non-operative treatment.…”

Section: Introductionmentioning

confidence: 99%

The Treatment of Axillary Odor: A Network Meta-Analysis

Sun

Wang

et al. 2019

Med Sci Monit

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Background Axillary osmidrosis (AO) is common in plastic surgery. But there is no perfect way to treat AO. We systematically compared the efficacy of 10 AO treatments with network meta-analysis in order to provide reference for the clinical treatment of axillary odor. Material/Methods Chinese and English databases were searched by computer. Some relevant studies were collected for network meta-analysis. Results We identified 56 studies, including a total of 8618 patients for meta-analysis. The network meta-analysis showed that 21 out of 45 pairs of 10 AO treatments had no statistical significance. In statistical comparison, subcutaneous curettage and swelling suction subcutaneous pruning were better than a single treatment. In addition, the effects of both laser and electric ion therapy were inferior to those of other treatments. The order of therapeutic effects predicted by surface under the cumulative ranking (SUCRA), curve was swelling aspiration+subcutaneous pruning >subcutaneous pruning >subcutaneous curettage+subcutaneous pruning >spindle excision >botulinum toxin A injection >swelling aspiration >subcutaneous curettage >YAG laser therapy >CO 2 laser therapy >electric ion therapy. Conclusions In operative treatment of AO, swelling aspiration+subcutaneous pruning is the best operative treatment, and botulinum toxin A injection is the best in non-operative treatment. Overall, the effect of surgical treatment was more significant than that of non-surgical treatment.

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Monte Carlo study of spatial resolution of the scintillation camera

Ouyang

Chen

2011

Sci. China Technol. Sci.

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The aim of this study was to evaluate the influence of different entrance surface treatments of the scintillator on the intrinsic spatial resolution of a scintillation camera. The primary scintillation light reflection on the entrance surface of a scintillator may be affected by the optical coating of the entrance surface, resulting in either spatial resolution or system detection efficiency degradation. A Monte Carlo simulation model, based on Geant4 codes, was developed in order to study the scintillation light transportation in the scintillator with an entrance surface of various optical coatings. The results demonstrated that the application of retro-reflector on entrance surface of the scintillation crystal can significantly improve the intrinsic spatial resolution of the scintillation camera. The physical mechanism of the improvement of spatial resolution is explored.surface treatments, gamma camera, spatial resolution, Monte Carlo study Citation:Zhu J, Ouyang X P, Chen D. Monte Carlo study of spatial resolution of the scintillation camera.

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Study of the characteristics of a scintillation array and single pixels for nuclear medicine imaging applications

Abstract: Study of the characteristics of a scintillation array and single pixels for nuclear medicine imaging applications * ZHU Jie( ) 1,2;1) MA Hong-Guang( ) 1 MA Wen-Yan( )ZENG Hui( ) 2 WANG Zhao-Min( ) 2 XU Zi-Zong( ) 2

Cited by 3 publications

References 9 publications

Feasibility of a CdTe-based SPECT for high-resolution low-dose small animal imaging: a Monte Carlo simulation study

Feasibility of a CdTe-based SPECT for high-resolution low-dose small animal imaging: a Monte Carlo simulation study

The Treatment of Axillary Odor: A Network Meta-Analysis

Monte Carlo study of spatial resolution of the scintillation camera

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