The Treatment of Axillary Odor: A Network Meta-Analysis

Abstract

Background Axillary osmidrosis (AO) is common in plastic surgery. But there is no perfect way to treat AO. We systematically compared the efficacy of 10 AO treatments with network meta-analysis in order to provide reference for the clinical treatment of axillary odor. Material/Methods Chinese and English databases were searched by computer. Some relevant studies were collected for network meta-analysis. Results We identified 56 studies, including a total of 8618 patients for meta-analysis. The network meta-analysis showed that 21 out of 45 pairs of 10 AO treatments had no statistical significance. In statistical comparison, subcutaneous curettage and swelling suction subcutaneous pruning were better than a single treatment. In addition, the effects of both laser and electric ion therapy were inferior to those of other treatments. The order of therapeutic effects predicted by surface under the cumulative ranking (SUCRA), curve was swelling aspiration+subcutaneous pruning >subcutaneous pruning >subcutaneous curettage+subcutaneous pruning >spindle excision >botulinum toxin A injection >swelling aspiration >subcutaneous curettage >YAG laser therapy >CO 2 laser therapy >electric ion therapy. Conclusions In operative treatment of AO, swelling aspiration+subcutaneous pruning is the best operative treatment, and botulinum toxin A injection is the best in non-operative treatment. Overall, the effect of surgical treatment was more significant than that of non-surgical treatment.

Clinical efficacy of microwave in the treatment of axillary osmidrosis and primary hyperhidrosis

“…Currently, AO and PH are intervened mainly through surgical treatment, oxybutynin, and botulinum toxin A injection. However, surgical treatment may generate compensatory hyperhidrosis to some degree in all patients, while botulinum toxin A injection usually maintains shortly and needs to be treated at regular intervals 3,4 . Clinicians are constantly on the lookout for treatments that are safer, more effective, and last longer.…”

Power‐assisted rotary cutter with negative pressure suction through small incision for axillary osmidrosis

“…At present, there are two treatments for axillary osmidrosis, nonsurgical treatment and surgical treatment 4 . Nonsurgical treatment includes antiperspirant and local injection of botulinum toxin, but the effect is not lasting 5 .…”

“…3 At present, there are two treatments for axillary osmidrosis, nonsurgical treatment and surgical treatment. 4 Nonsurgical treatment includes antiperspirant and local injection of botulinum toxin, but the effect is not lasting. 5 Surgical treatment has many different surgical methods, but the common purpose is to remove secretory tissues such as sweat glands under armpit skin, so as to achieve the purpose of treatment.…”

Treatment of Axillary Osmidrosis by Rebalancing Skin Microecology With Lactobacillus bulgaricus

“…We investigated the effects of Lactobacillus bulgaricus treatment on the armpit microecological environment and its efficacy for AO treatment. Efficacy was evaluated by comparing the changes in the microecological environment and AO severity at targeting sites before and after treatment using previously described methods (Sun et al, 2019 ).…”