Study of Prophylactic Action of Griseofulvin—Human Experimental Infection with Trichophyton Concentricum

Tinea imbricata in the Americas

“…The drug of choice is still griseofulvin (used in many studies) [35][36][37], and nowadays also terbinafine; however, the disease has high rates of recurrence and most patients cannot achieve a total cure. Azole agents have a poor effect on this disease [37,38]; one comparative study among griseofulvin, terbinafine, itraconazole and fluconazole demonstrated that patients treated with fluconazole experienced no significant remission of the disease, whereas this period was of short duration in those that used itraconazole; on the contrary, griseofulvin and terbinafine showed the longest remission period in patients treated with them [3].…”