Study of prescribing pattern of antimicrobial agents in indoor patients of a tertiary care hospital

Abstract

Background: To evaluate prescribing pattern of antimicrobial agents in indoor patients of medicine and surgery department of SBH Government Medical College, Dhule. Methods: This was a retrospective cross sectional study carried over a period of 3 months. The patients who were admitted and received antimicrobial therapy in department of Medicine and Surgery were randomly selected and included in the study. The case record sheet and drug chart were obtained from Medical Record Section of the Hospital. The data was collected using case record form specially prepared for the study. The cases were categorised according to slightly Modified Kunin’s Criteria. Results: Total numbers of patients receiving antimicrobial therapy were 130 in medicine department and 93 in surgery department. Most commonly prescribed antimicrobial agent was cefotaxime (21.7%) in medicine and metronidazole in surgery (30.6%) department. The average number of antimicrobials per patient was found to be 1.7 and 3.02 in medicine and surgery department respectively. The switch on therapy from parenteral to oral route was employed in 16.15% patients in medicine department and 11.82% patients in surgery department. As per Kunin’s modified criteria, 66.2% and 58.06% patients received antimicrobial therapy appropriately in Medicine and surgery department respectively. Conclusion: This study highlights the problem of over-prescription of antibiotics and a trend towards polypharmacy. The interventions to rectify the problem of inappropriate use of antimicrobial agents are needed to make therapy more rational and cost effective. [Int J Basic Clin Pharmacol 2013; 2(3.000): 281-285

Antibiotic Utilization Pattern at the Surgery Department of a Tertiary Care Hospital

“…In this study, the average number of antimicrobials prescribed in surgery department was 3 per patients. This is similar to that reported by Deshmukh, prescribing pattern of antimicrobial agents in indoor patients of SRTR Government Medical College, Maharashtra, which was 3.02 [12]. Another study conducted in Dr. B.R.…”

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“…This report is somewhat similar to reported by Deshmukh vs et al 27 was 66.2%. A study carried out by Pavani V et al, showed that 80% of patients received antimicrobial agents' appropriately 28 .…”

Drug utilization study of some antibiotic in indoor setting at tertiary care teaching hospital in Central India: a descriptive study

“…19 But result of present study was in approximate correspond to observation by Bharti Mahajan et al which had 3.36 AMA per prescription. 20 3.02 is the average number of AMA per prescription in study of Deshmukh VS et al 8 Most of the prescriptions had injectable antibiotic preferably as cases were from indoor setting. Majority of antibiotic were prescribed from National List of Essential Medicine, India and in WHO Model List of Essential Medicines (17 th edition).…”

“…The fear of physician whether he is missing any occult infection also makes him to use antibiotic umbrella for protecting him and his patient. 8 In order to get breakthrough from the irrational pattern of prescribing behaviour of antibiotic this study is done.…”

“…Most of the studies shows results similar to present study. 4,8,[10][11][12][13] Only 6 (2%) number of cases had Culture and Sensitivity test done. These suggest that in most of the prescriptions criteria for initial selection of antibiotic was Empirical.…”