Study of Pathological Variations of Solitary Thyroid Nodule

Mamun, Abdullah Al; Alam, Zahedul; Islam, MM Shahin Ul; Mahamud, Mashuque; Rahman, M. M. Hafizur; Aich, Mani Lal

doi:10.3329/bjo.v24i2.44154

Cited by 9 publications

(15 citation statements)

References 14 publications

(14 reference statements)

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“…Papillary carcinoma was more common than follicular carcinoma. This finding is supported by the work of Al Mamun et al 12 Lin et al has reported that 23.3% of nodule were malignant and papillary carcinoma was more common which partially support our study. 13 Khadilkar UN et al has reported that non neoplastic lesions like involuting nodules were common which support our study.…”

Section: Discussionsupporting

confidence: 92%

A clinicopathological evaluation of solitary nodule in thyroid; a retrospective observational hospital based study

Lakshmi¹,

Reddy²

2020

Int Surg J

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Background: The solitary node in thyroid is a palpably discrete swelling within an apparently normal thyroid gland. It is usually a benign lesion but from clinical standpoint the possibility of neoplastic disease is of major concern for surgeon and patient. AS there is variability in the conclusion of various authors and there is no work about clinicopathology of solitary nodules of thyroid in our region. Present study has been designed to evaluate the epidemiology, fine needle aspiration cytology and incidence of malignancy in solitary nodule.Methods: As per exclusion and inclusion criteria 80 patients with solitary nodule of thyroid were included in this study. Various data like age, sex, family history, duration of nodule, site and size of nodule were recorded. Thyroid function test, fine needle aspiration cytology and ultrasonographic finding were recorded from case record.Results: Out of all histopathological finding of nodules follicular adenoma was most common followed by multinodular goitre (25%) and Adenomatous goitre (7.5%). Carcinoma was present in (17.5 %) and thyroiditis is 7.5% patients.Conclusions: Most of the patients were Euthyroid and benign condition was more common than malignancy. Follicular adenoma was most common among benign lesion and papillary carcinoma was more common neoplasm. Most of the patients required hemithyroidectomy.

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Section: Discussionsupporting

confidence: 92%

A clinicopathological evaluation of solitary nodule in thyroid; a retrospective observational hospital based study

Lakshmi¹,

Reddy²

2020

Int Surg J

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“…We had a low incidence of cancer in our study and therefore, very low incidence of dysphagia, hoarseness of voice and stridor. 5,6 Lymphadenopathy correlated with the presence of malignancy with 8 of the 13 patients showing an FNAC proof of malignancy. We can conclude that presence of lymphadenopathy in the presence of a thyroid swelling has high possibility of a sinister presence, usually Papillary carcinoma and every effort should be made by the clinician both clinically and US scan wise to discover lymphadenopathy.…”

Section: Discussionmentioning

confidence: 95%

Clinicopathological study of swellings of the thyroid gland with an emphasis on multinodular goitre

Desai¹,

Srivastava

Amenha³

2023

PJMS

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Many suggest that clinical examination is the best tool to detect the nodules of the thyroid gland. They also suggest that ultrasound of the thyroid gland should be used only to monitor any changes in the size of the nodule of the thyroid. To study swellings of the Thyroid gland with an emphasis on multinodular goitre.The study is prospective, involving all the patients of thyroid swelling. All thyroid swelling cases were subjected to FNAC. The type of thyroidectomy was based on the size and type of thyroid whether neoplastic or non-neoplastic. All the 102 patients were treated by surgeries like hemithyroidectomy, subtotal and total thyroidectomy following FNAC. Majority of the study subjects were in the age group of 20-29 years i.e. 29.5%. In this study most common consistency of thyroid swelling was found to be soft in 61 patients, firm in 22 and hard in 19. Lymph nodes were present in 13 patients (12.75%). 95.1% (97) of patients were euthyroid, four were hypothyroid and one was hyperthyroid. most common FNAC finding was colloid nodule in 61.8% of the cases followed by adenoma in 12.8% of the cases. Most common clinical diagnosis was solitary nodular goitre in 49% of the cases followed by multinodular goitre in 24.5% of the cases. Most common type of surgery performed was Hemithyroidectomy in 50.9% of the cases Most common complication was bleeding which occurred in only three cases. FNAC is a very useful and indispensable test in the diagnosis of thyroid lesions.

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“…10 They are 3-4 times more frequent in women than men. 11 An increase in prevalence rate in women was observed particularly in age group 21-30 years which might be associated with infertility, pregnancy and other complications. 12 Most of the thyroid nodules are benign and fewer than 5% of them are actually malignant.…”

Section: Introductionmentioning

confidence: 99%

Clinicopathological study of asymptomatic thyroid swelling and its correlation with thyroid function tests

Bhargava

Faiz

Shakeel

et al. 2019

Int J Otorhinolaryngol Head Neck Surg

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Background: Thyroid swelling without symptomatic manifestation is common occurrence and could affect 5 to 20% patients in endemic areas. Majority of them are non neoplastic and may not require surgery. Less than 5% of thyroid nodules are malignant.Methods: Present study was conducted to correlate clinical findings, HRUSG findings, thyroid profile and FNAC findings in patients of asymptomatic thyroid swelling. Results: Proportion of euthyroid patients was higher compared to hyperthyroid and hypothyroid diagnosed as colloid goiter on FNAC findings (82.4% vs. 0.0% and 12.9%). Proportion of hypothyroid was higher compared to euthyroid and hyperthyroid diagnosed as Follicular adenoma (3.2% vs. 0.0% and 1.2%) and colloid goiter with cystic changes (48.4% vs. 0.0% and 10.6%). Proportion of hyperthyroid compared to hypothyroid and euthyroid patients were higher diagnosed as thyroiditis (75.0% vs. 32.3% and 5.9%) and papillary/medullary CA (25.0% vs. 3.2 and 0.0%). A statistically significant association of FNAC diagnosis and thyroid profile of patients with asymptomatic thyroid swelling was found.Conclusions: The present study showed that thyroid dysfunction could play a significant role in determining the underlying pathology behind thyroid swelling and must be evaluated at the earliest using thyroid function tests as the first line of diagnostic tool. In case of suspected thyroid profile; USG neck and FNAC should be done. In view of lack of studies correlating thyroid and clinicopathological profiles of thyroid swellings, further studies to potentiate the present study findings are recommended.

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Study of Pathological Variations of Solitary Thyroid Nodule

Cited by 9 publications

References 14 publications

A clinicopathological evaluation of solitary nodule in thyroid; a retrospective observational hospital based study

A clinicopathological evaluation of solitary nodule in thyroid; a retrospective observational hospital based study

Clinicopathological study of swellings of the thyroid gland with an emphasis on multinodular goitre

Clinicopathological study of asymptomatic thyroid swelling and its correlation with thyroid function tests

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