Study of morphological spectrum of gallstone and bacteriology of bile in cholelithiasis

Gupta, Ashutosh; Ramteke, Sushma; Kanwar, K; Soni, Pradeep

doi:10.18203/2349-2902.isj20164402

Cited by 4 publications

(14 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…11,12 In our study, among the type of gallstones, cholesterol type was seen in 68% cases. This was not in accordance with previous study reports of Gupta et al 1 In their study, mixed type of gallstone was more predominant (50%) among the other types.…”

Section: Discussioncontrasting

confidence: 95%

“…In our study, majority of the patients were between 41-50 years (38%). This was in accordance with the findings of Gupta et al 1 The increased incidence of gallstone with increase in age is probably due to decrease of cholesterol reductase activity and increase of HMG co-A reductase activity. 9 Female preponderance (69%) was observed in our study.…”

Section: Discussionsupporting

confidence: 93%

“…9 Female preponderance (69%) was observed in our study. Similar observation was made by Gupta et al and Lokesh et al 1,10 The high evidence of gallstones in females might be due to changes in female sex hormones with increase in age and due to the sedentary habits of most women in India. 11,12 In our study, among the type of gallstones, cholesterol type was seen in 68% cases.…”

Section: Discussionsupporting

confidence: 80%

See 2 more Smart Citations

Study of associationship between gall stone composition and bacteriological spectrum in chronic calculous cholecystitis

Singh

Chandra

et al. 2019

Int Surg J

View full text Add to dashboard Cite

Background: Chronic calculous cholecystitis is the benign disease affecting the gallbladder, frequently female population of middle age. This study was done with the objective of study the composition of gall stones, microbiological spectrum and their association in chronic calculous cholecystitis patients.Methods: This is a prospective study done on 131 cases of chronic calculous cholecystitis admitted in the department of General Surgery (DNB), K.K. Hospital, Lucknow for cholecystectomy during January 2018 to January 2019. 31 patients were excluded from the study based on exclusion criteria. USG of abdomen was done in all 100 cases. All patients underwent either open cholecystectomy (OC) or laparoscopic cholecystectomy (LC).During cholecystectomy bile was aspirated and was sent to laboratory for culture. Gallstone retrieved from the specimen and was classified based on morphology.Results: Out of 100 cases, 76 cases underwent LC and 24 cases were done with OC. Female dominance was seen in the study (69%). The predominant type of gall stone in present study was cholesterol (68%). The bile culture test was positive in 20% of cases. The most common isolated microorganism was E. coli (50%). No significant association was observed between composition/type of gall stone and isolated microorganisms in bile (p=0.126).Conclusions: The result concluded that chronic calculous cholecystitis was more common in females of middle age group. Bile culture was positive in 20% cases and E. coli was the common organism isolated. Identification of the type of organism is crucial for early management of the disease condition.

show abstract

Section: Discussioncontrasting

confidence: 95%

Section: Discussionsupporting

confidence: 93%

Section: Discussionsupporting

confidence: 80%

See 1 more Smart Citation

Study of associationship between gall stone composition and bacteriological spectrum in chronic calculous cholecystitis

Singh

Chandra

et al. 2019

Int Surg J

View full text Add to dashboard Cite

show abstract

“…Studies by Steward et al showed most common as Pseudomonas followed by E. coli, Klebsiella, Enterobacter and Enterococcus. 13 Sushma et al showed 90% E. coli and rest Klebsiella 23. Syed et al reported similar frequency of organisms as that of present study 14.…”

supporting

confidence: 80%

“…13 Ramteke et al reported about 20% stone culture positivity with 4.7% culture positive cholesterol stone, 25.9% culture positive pigment stones and 100% positive mixed stone culture. 23 The morphological classification used here is different from the current study. The percent of culture positive stones is comparable to the present study.…”

Section: Discussionmentioning

confidence: 87%

Bacteriological study of nidus of gallstones

et al. 2019

View full text Add to dashboard Cite

Background: Gallstone disease is common worldwide and majority of patients undergo surgical management. Since the advent of laparoscopic cholecystectomy surgeons has become less interested in its aetiology. Infection is a major factor in the formation of gallstones. There are many infective complications reported of gallstones spilled during cholecystectomy. Presence of bacteria or its DNA by microscopy does not prove the infective potential of such stones. Thus culture of the nidus of the gallstone is the gold standard method to identify any potentially infective bacteria within and to predict the infective potential of gallstones.Methods: Cross sectional study done in seventy patients admitted for elective cholecystectomy for a period of 24 months from August 2016 to July 2018 in Department of Surgery, Regional Institute of Medical Sciences, Imphal, India.Results: Of the 70 stones cultured for bacteria, 52 (74.3%) were sterile and 18 (25.7%) were positive for bacteria, among which 16 stones showed mono-microbial growth while 2 showed poly-microbial growth. Most commonly isolated organism was E. coli and Klebsiella followed by Pseudomonas, Enterococcus and Staph aureus.Conclusions: Moynihan‘s aphorism “gall stone is a tomb erected in the memory of the organism within it”, suggest bacteria inside gallstone to be dead but this study proves that bacteria can be viable inside gallstone and its complete retrieval should be done in case of spillage which may help in avoiding complications.

show abstract

Etiology and chemical composition of gall stone disease: a prospective observational study from the developing world

et al. 2021

View full text Add to dashboard Cite

Background: Aim of the study was to assess the etiology and determine the chemical composition of gallstones in our population.Methods: This was a prospective observational study conducted at GMC Srinagar from 2018 to 2020. One hundred patients having gall stone disease were enrolled into the study and after cholecystectomy was performed the stones chemical composition was analyzed by fourier-transform infrared (FTIR) spectroscopy. The data was collated and analysed.Results: 54 patients had mixed stones with chemical composition of cholesterol, calcium carbonate and calcium bilirubinate; 39 had cholesterol stones and 7 patients had pigmented stone with chemical composition of cholesterol, calcium carbonate and calcium bilirubinate.Conclusions: Our results suggest that cholesterol, either singularly or in combination with calcium carbonate or bilirubin is a common component of gall stones in our population.

show abstract

Study of morphological spectrum of gallstone and bacteriology of bile in cholelithiasis

Cited by 4 publications

References 8 publications

Study of associationship between gall stone composition and bacteriological spectrum in chronic calculous cholecystitis

Study of associationship between gall stone composition and bacteriological spectrum in chronic calculous cholecystitis

Bacteriological study of nidus of gallstones

Etiology and chemical composition of gall stone disease: a prospective observational study from the developing world

Contact Info

Product

Resources

About