Background: Gallstone disease is common worldwide and majority of patients undergo surgical management. Since the advent of laparoscopic cholecystectomy surgeons has become less interested in its aetiology. Infection is a major factor in the formation of gallstones. There are many infective complications reported of gallstones spilled during cholecystectomy. Presence of bacteria or its DNA by microscopy does not prove the infective potential of such stones. Thus culture of the nidus of the gallstone is the gold standard method to identify any potentially infective bacteria within and to predict the infective potential of gallstones.Methods: Cross sectional study done in seventy patients admitted for elective cholecystectomy for a period of 24 months from August 2016 to July 2018 in Department of Surgery, Regional Institute of Medical Sciences, Imphal, India.Results: Of the 70 stones cultured for bacteria, 52 (74.3%) were sterile and 18 (25.7%) were positive for bacteria, among which 16 stones showed mono-microbial growth while 2 showed poly-microbial growth. Most commonly isolated organism was E. coli and Klebsiella followed by Pseudomonas, Enterococcus and Staph aureus.Conclusions: Moynihan‘s aphorism “gall stone is a tomb erected in the memory of the organism within it”, suggest bacteria inside gallstone to be dead but this study proves that bacteria can be viable inside gallstone and its complete retrieval should be done in case of spillage which may help in avoiding complications.
Background: Young adults with hypertension have a higher lifetime risk of cardiovascular diseases. Global evidence suggests a significant role of diet and lifestyle risk factors on hypertension among the young adult (aged 18–39 years) hypertensive population. Aim: The purpose of this study was to look for the association of diet and lifestyle risk factors with young adult hypertensives. Results: This study reports the prevalence of young adult hypertension based on a national representative sample based on the National Family Health Survey (NFHS-4) data and the association of behavioral risk factors with young adult hypertension. The survey adopted a two-stage stratified random sampling. The outcome variable was hypertension, whereas the exposure variables were various diet and lifestyle factors. The prevalence of young adult hypertension in India was 12.4% among men and 8.2% among women. Sikkim had the highest prevalence among both sexes. Lower prevalence was seen in the states of Delhi and Kerala. Marital status, body mass index, eating meat, alcohol intake, and taking coffee or tobacco 30 min before BP measurement were found to be associated factors that put both the sexes at risk of developing hypertension. The wealth index was concluded as a risk factor only in men while the level of education came out to be a risk factor only in females. Conclusion: This study is the first from India which gives a recent estimate of prevalence of young adult hypertension by state and individual level characteristics in addition to national level estimates for India.
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