Study of maternal influences on fetal iron status at term using cord blood transferrin receptors

Abstract

Conclusions-Maternal iron depletion is associated with reduced fetal iron stores but no change in free iron availability. Smoking is associated with increased fetal iron requirements for erythropoiesis. (Arch Dis Child Fetal Neonatal Ed 2001;84:F40-F43)

Impact of twice weekly versus daily iron supplementation during pregnancy on maternal and fetal haematological indices: a randomized clinical trial

“…Higher levels of ferritin in cord blood can be attributed to active transport of iron to the fetus. Nevertheless, several studies have shown that in severe maternal anaemia these active pathways may fail [22,23].…”

Does Maternal Iron Deficiency Affect Iron Status Of the Newbornsa and Early Infants ?

“…Yapılan bazı çalışmalarda, gebelerdeki demir eksikliğinin, fetus ve infarıtın demir durumunu etkilediği, prematür doğum prevalansını artırdığı, uzun dönemde büyüme ve gelişme geriliğine neden olabileceği gösteril-miştir (5)(6)(7)(8). Bazı çalışmalarda da annenin demir durumunun bebeğin demir durumuna etkisi olmadığı, bebeklerin demir depolannın ilk dört ay için yeterli olduğu bildirilmiştir (9-1 1).…”

Soluble Transferrin Receptor levels of Apparently Healthy Adults in Port Harcourt, Nigeria

“…[6,7] Sweet et al reported that sTfR measurement could replace other assays for iron deficiency state especially in subclinical iron deficiency present in their study population which was undetected by these other assays. [8] There is no difference between sTfR concentrations in healthy males and females, [9,10] but the values are higher in children compared to adults. [11] However, Blacks have a higher sTfR concentration than non-blacks.…”

“…[11] However, Blacks have a higher sTfR concentration than non-blacks. [12] This difference may be related to the well-known but unexplained difference in haemoglobin concentrations in Blacks and Caucasians.Therefore, misdiagnosis of Some studies have also shown that sTfR is increased in blood donors, [13] during physical exercise, [14,15] cigarette smoking, [8] and high altitude, [16] where reduced oxygen tension necessitates increased erythropoiesisbut is reduced by ascorbic acid administration and iron supplementation. [17,18] A blood donor loses about 200-250 mg of iron with every unit of 450mls of blood donated.…”