Study of low noise multichannel readout electronics for high sensitivity PET systems based on avalanche photodiode arrays

Habte, Frezghi; Levin, Craig S.

doi:10.1109/tns.2004.829599

Cited by 10 publications

(3 citation statements)

References 17 publications

(13 reference statements)

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“…The improvements of computing, especially the improvement of the ADC, accelerate the development of PET system and lead to the optimization and revolution of the frontend circuit. With the development of CMOS technology, such as decrease of the minimum line width and threedimensional integrated technology, the performance, design method and cost of the front-end specific chip are advanced constantly [5,6]. This paper discussed a novel front-end readout circuit architecture and design challenges for PET imaging systems, and gave the simulation results for signals flow.…”

Section: Introductionmentioning

confidence: 99%

Design of a Novel Front-End Readout ASIC for PET Imaging System

Zeng¹,

Wei²,

Shen³

et al. 2013

JSIP

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The architecture of a multi-channel front-end system is important for realizing a high-resolution PET system. We propose a novel front-end readout electronic system with TDC to deal with time information for PET system which can easily design the timing control. Each channel consists of a charge preamplifier, slow/fast shaper, discriminator and a analog memory. There are a ADC and a TDC to process the energy information and time information for each channel at the same time. In this paper, the whole system signals flow is all simulated by MATLAB. The simulation results show that the proposed system can process slender current from the detector and achieve the energy and time information. The proposed architecture can be applied to high-resolution PET imaging systems with multi-channel ASICs.

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Section: Introductionmentioning

confidence: 99%

Design of a Novel Front-End Readout ASIC for PET Imaging System

Zeng¹,

Wei²,

Shen³

et al. 2013

JSIP

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“…The detector is expected to reduce parallax error effectively because of its short data sampling interval in depth direction. It would be accordingly advantageous to use in a high sensitive PET system of large solid angle and a PET system dedicated to breast or prostate cancer [2][3][4][5][6][7][8], MR-PET [9][10][11][12], and optical-PET [13], which all need a close detector setting to the object.…”

mentioning

confidence: 99%

Optimization of Crystal Arrangement on 8-Layer DOI PET Detector

Inadama¹,

Murayama²,

Tsuda³

et al. 2006

2006 IEEE Nuclear Science Symposium Conference Record

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Previously, we proposed an 8-layer depth-ofinteraction (DOI) encoding method for a PET detector and proved its validity. The layer of interaction is identified by hybrid method: scintillation light control by the original reflector arrangement for 4-layer DOI encoding and pulse shape discrimination for 2-layer DOI encoding.In the 8-layer DOI detector, four layers then consist of the scintillator of different pulse shape from another scintillator for the other four layers. The two kind crystal layers can be arranged in two ways: stacked alternately (LSLS) or set in the upper and lower four layers (LLSS). Since the two crystal arrangements are expected to show different detector performance, we investigated the difference to understand the characteristics of the DOI detector for its optimization. Gd 2 SiO 5 (GSO) crystals of 0.5 mol% Ce dopant and 1.5 mol% Ce dopant were used for the measurement. The former is in dimensions of 2.9 mm × 2.9 mm × 3.75 mm and the latter is 2.9 mm × 2.9 mm × 3.6 mm, respectively. The experimental results show better performance of the LLSS arrangement in pulse shape discrimination, while inferior in the 4-layer DOI encoding. There was no particular difference between the two crystal arrangements in light output and energy resolution of each layer.

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“…In concert with other efforts to develop an ASIC for LSO-APD-based PET detectors [1][2][3][4][5][6][7][8][9], we are developing an ASIC as part of a small animal PET system. Some of the unique features of our ASIC include the ability to process signals of either positive or negative polarity, an on-chip, "winner-takeall" multiplexer, and an input for processing the coincident trigger from other detectors.…”

Section: Introductionmentioning

confidence: 99%

An Application-Specific Integrated Circuit for Positron Emission Tomography

Christian

Dokhale

Lawrence

et al.

IEEE Nuclear Science Symposium Conference Record, 2005

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Improving the performance of positron-emission tomography (PET) systems for small animal imaging requires the use of high-speed detectors, such as a Lutetium Oxyorthosilicate (LSO) crystal coupled to avalanche photodiodes (APDs). We have developed an application-specific integrated circuit (ASIC) for reading out the multiple channels of an LSO-APD detector module for use in a small animal PET system.In this work, we characterize the performance of the ASIC, referred to as the AE172 chip. The AE172 can accommodate both positive and negative input signals, with a programmable conversion gain that ranges from 2.8 mV/fC to 21 mV/fC. The ASIC channels exhibit a linear response and an equivalent noise charge (ENC) of ~2000 electrons, RMS. The timing jitter depends on the amplitude of the input signal; and is less than 1 ns for test signals greater than 100,000 electrons.Connecting the ASIC to a linear APD detector reduces the relative readout noise to 26 electrons referenced to the input of the APD, which is operated at a gain of ~200. An LSO-APD-ASIC detector achieves an energy resolution of 13% for the 511 keV annihilation photons from a 22 Na source, and a coincident timing resolution of ~13 ns.

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Study of low noise multichannel readout electronics for high sensitivity PET systems based on avalanche photodiode arrays

Cited by 10 publications

References 17 publications

Design of a Novel Front-End Readout ASIC for PET Imaging System

Design of a Novel Front-End Readout ASIC for PET Imaging System

Optimization of Crystal Arrangement on 8-Layer DOI PET Detector

An Application-Specific Integrated Circuit for Positron Emission Tomography

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