Study of incidence of malignancy in clinically benign thyroid swelling

Abstract

Also, patients in the younger age group had bigger spleens as compared to old (65% vs. 42%). 11 patients also had significant lymphadenopathy, most commonly involving the inguinal group. Hemoglobin (Hb) level was in the range of 5.5-13.0 g/dl (9.4 ± 4.8). Mean Hb levels did not differ much among the three phases [Table 2]. Average platelet count in younger group was significantly higher than in the older age group (mean 3.63 × 10 5 / µl ± 1.99 vs. 2.62 × 10 5 /µl ± 1.40; P = 0.01) [Table 2]. Available data suggest that the epidemiology of CML is different in the Indian subcontinent and in other developing countries from that of the rest of the world. [3] In our study, the median age was 35 years (range 11-70 years) which is significantly lower than reported in European [4] (median age 55 years) and American literature [5] (median age 66 years). In the study by Bhutani et al., the median age of onset is 38 years in India [2] while in a regional study in Pakistan mean age was 37.87 years which is quite less than the age of presentation in west. [6] Shorter life expectancy, Table 2: Peripheral blood findings in patients according to phases Value CP (n=39) AP (n=10) BC (n=19) Hb (g/dl) range 5.5-13.0

Association between multi nodular goitre and thyroid malignancy at a tertiary care centre

“…3 A more recent Indian study Karthik et al has pointed out a slightly lower rate of 5.8%. 4 Similar studies on the prevalence of malignancy they detected were as follows-Rehman et al 3.87%, Nanjappa et al 12%, Hanumanthappa et al 10%. [5][6][7] The prevalence of malignancy in multi nodular goitre in the present study, thus well correlates with the results previously obtained.…”

Thyroid Malignancy among Fine Needle Aspiration Cytology of Thyroid Lesions in a Tertiary Care Centre

“…This aligns with the investigations conducted in India, where PTC accounts for a prevalence range of 60-70%, and in Nepal, where it represents a substantial 77.42%. 7 , 9 PTC may be more prevalent due to its relation with radiation exposure and high iodine consumption. 10 In alignment with the predominant findings across various studies, our research also concurs that thyroid cancers predominantly affect the female population.…”