Study of high amylose corn starch as food grade enteric coating in a microcapsule model system

Technology and potential applications of probiotic encapsulation in fermented milk products

“…Therefore, gel-beads maintain their shape and structure (Truelstrup-Hansen et al, 2002). Using resistant starch as a capsule material makes beads resistant against enzymatic digestion (Dimantov et al, 2003). Sometimes it is necessary to use especial types of hydrophobic components for encapsulation to make the beads tolerant against the high moisture conditions of products (Truelstrup-Hansen et al, 2002).…”

“…Furthermore, increasing capsule diameter leads to decreasing its digestibility by pancreatic enzymes. Increasing of beads diameter especially when resistant starch is used for capsule formation should be under attention because this component is resistant to enzymatic digestion of pancreas (Dimantov et al, 2003). Research relevant to the concentration of capsule-making solutions has revealed that raising concentration of alginate solution from 0.75 % to 1.8 % has noticeable effects on L acidophilus viability under the simulated gastric conditions; but at >2 %, it was impossible to generate spherical and homogeneous beads due to increase in solution viscosity and decrease in its of mass diffusivity (Chandramouli et al, 2004).…”

Films from resistant starch-pectin dispersions intended for colonic drug delivery

“…High amylose starch (HAS), a modified starch containing high content of amylose, has been considered as a favorite material to obtain high contents of RS (Dimantov, Greeberg, Kesselman, & Shimoni, 2003;Fishman, Coffin, Unruh, & Ly, 1996;Htoon et al, 2009), because the amylose forms an amorphous matrix in which the crystallites are embedded and thus protected against the fast exposition to digestive enzymes (Cui & Oates, 1997).…”

Going Natural: Using polymers from nature for gastroresistant applications

“…In terms of gastrointestinal drug delivery, starch has been mainly explored for colonic targeting (Kotla et al, 2014;Norman, 2011). High-amylose starch is highly resilient to gastric conditions (pH 1.6, 0.1M HCl, 2 h) and also at neutral pH (pH 7.0, phosphate buffer 0.1 M, 3 h), however when pancreatic enzymes are present, amylose is enzymatically digested, causing the disintegration of the dosage form (Dimantov et al, 2004). Carboxymethyl high amylose starch (CM-HAS) has been used to produce oral vaccines for the delivery of F4 fimbriae to the colon and also as a complex with lecithin for a mesalazine-based colonic delivery system (Mihaela Friciu et al, 2013).…”