Study of endometrial Status of Patients with Abnormal Uterine Bleeding in Patan Hospital

Abstract

BackgroundAbnormal uterine bleeding may be defined as changes in frequency of menstruation, duration of flow or amount of blood loss. Early accurate diagnosis and proper treatment is essential to prevent progress to endometrial cancer. ObjectiveThis study was done to evaluate the histopathology of endometrium for identifying the endometrial causes of abnormal uterine bleeding. MethodThis was a retrospective study done in department of pathology, Patan Hospital from 1 August 2011-to 31 July 2012; total 413 cases were included in this study. ResultsThe age of the patients ranged from 19 to 70 years. The most common clinical presentation was menorrhagia (47.46%), followed by continuous bleeding (14.04%) and metrorrhagia (13%).The commonest histopathological diagnosis was secretory endometrium 128 cases (30.99%), followed by proliferative endometrium 91 cases (22.03 %). Secretory endometrium was most commonly (52 cases) observed in 41-50 years age group followed by 43 cases in 30-40 years age group. Similarly proliferative endometrium was also most commonly seen in 41-50 age group (44 cases) followed by 31-40 years of age group (32cases). Malignant disease was most commonly seen in 51-60 years age group. ConclusionsAbnormal uterine bleeding is most common in 21-30 years age group.The most common clinical presentation is menorrhagia followed by continuous bleeding. Secretory endometrium is the most common histopathological findings. Malignancy is more common in postmenopausal group.

Histopathological Evaluation of Endometrium in Cases of Abnormal Uterine Bleeding- An Institutional Experience in a Tertiary Care Center

“…All the cases were categorized into reproductive (15-40 years), perimenopausal (41-50 years) and postmenopausal (>50 years) groups; done in accordance to studies by several authors. 3,10,11 There were 226 patients belonging to the reproductive age group (21-40 years). Proliferative endometrium was the dominant histological finding in this age group accounting for 51.8% followed by 32.3% of secretory endometrium; there were no cases of malignancy in this group.…”

A retrospective study of endometrial histopathology in abnormal uterine bleeding patients

“…Shrestha et al also showed that endometrial carcinoma is most commonly found in postmenopausal age group. 11 So, histopathological diagnosis of endometrium in AUB patients is an important and a necessary investigation for appropriate planning of optimal treatment in these patients and to prevent the development of endometrial carcinoma. 12 AUB in perimenopausal and postmenopausal patients is alarming and needs meticulous evaluation because it could be the only clinical symptom of endometrial carcinoma and preneoplastic conditions in these patients.…”