Study of donor deferral during blood donation: A single centre teaching hospital study

Abstract

Background: Safe blood transfusion can be a crucial lifesaving intervention in many clinical situations.For safe blood products donor selection is the first and foremost measure of blood donation. Objective:Aim of the study to determine the incidence and causes for deferral in blood donors. Materials and Methods: This cross-sectional retrospective study was done at Transfusion medicine department in Delta Medical College and Hospital, Bangladesh during 6 months period. In current study data were extracted from the register book and analyzed. Prospective donors were confidentially interviewed and examined and screened for causes of temporary and permanent deferral of blood donation. Data were presented as charts, table and analyzed with Microsoft Excel. Result: A total of 2215 directed donors were studied,of them, 1555 (73.52%) were male and 560 (26.48%) females. Predominantly blood donors belonged to 31–40 years of age group (38.01%). Out of 2115 directed donors, 423 (20%) were deferred. Deferral was significantly more likely in female. The most common cause for deferralwere history of anemia (27.66%). Other causes were antibiotic & medications, high blood pressure, low blood pressure, frequent donation, Positive HBsAg, HCV markers, suspected addiction, and vaccination. Conclusion: Effective measures are required for documenting the deferred donors and appropriate preventive intervention program should be undertaken for prevalent causes of deferrals, like low Hb, Infections with HBV etc. Anemia is the most prevalent reason of temporary deferral for blood donation in this region of Bangladesh. Other reasons were hypertension, hypotension,suspected addiction, vaccination etc. Bangladesh Journal of Medical Science Vol. 21 No. 03 July’22 Page: 645-647

Causes of Pre and Post-Donation Deferrals among Blood Donors, at Kwale Satellite Blood Transfusion Center, Kwale County, Kenya, 2018-2022.

“…Also, Hypertension was reported as a common cause of deferral at 11.15%. This nding is in agreement with other studies, which reported proportions of 12.3-14.6% [9][10][11]. Indeed, different rates for hypertension have been reported in different populations of prospective blood donors around the globe ranging from 5.8-29.4% [2,8,12].…”

“…Several studies have reported low hemoglobin as a major cause of pre-donation deferrals [2,3,[6][7][8]. Other studies documented hypertension as the cause of the pre-donation deferrals [2,[8][9][10][11][12], while yet another studies found hypotension to be a reason for pre-donation deferrals [11,13,14]. Other reasons for pre-donation deferrals includes: underweight, behavioral risks, low or high pulse rate, being on medication, age related reasons, blood group mismatch among others [2, 3, 9-12, 15, 16].…”

Profile of Blood Donors and Deferral Reasons in a Tertiary Care Centre in South India

“…One study by Haque et al [18] has deferred 4.26% donors due to wrong Blood group which is much lower than our study. These individuals were also included in the donor pool and they were added as a deferred donors.…”

“…Donor deferral rate in our study was 19.1% which was higher than many other studies from India. A study done by Haque et al [18] from Bangladesh had comparable deferral rates. The variation in deferral rate can be attributed to many causes like variation in donor selection criteria and type of donors.…”

“…Author Name Study period Deferral rate (%) Shastry et al [15] 13 years 5.6% Sundar et al [16] 3 years 6% Shrivastava et al [1] 12 years 11.5% Agnihotri [17] 1.5 years 11.6% R K Chaudary et al [9] 2 years 16.4% Bahadur et al [6] 2 years 9% Anegundi R. et al [11] 1 year 13.6% Haque et al [18] 6 months 20% H Gulen et al [19] 6 months 27.6% Koju et al [20] 4 years 9.5% Present study 4.5 years 19.1%…”