Blood is considered a scarce resource in the world. Many patients requiring transfusion do not have timely access to safe blood and many lives are lost because of this reason. According to the WHO Information Sheets, 2005 80% of the worldwide population has access to only 20% of safe blood. Aim- To analyse the donor profile and the need for voluntary blood donation drives. Methodology: A descriptive cross-sectional study conducted among blood donors attending the blood bank of a Tertiary care centre in South India from 2015 to 2019. Results: Out of 7979 blood donations, voluntary donors were only 8.5 % with most (97.8%) of the donors being males. The donors arriving at the blood bank were between 18 and 64 years of age. Of the voluntary donors, about 37% were first-time blood donors. The commonest available blood group was O positive (34.1%) and the least available was AB negative (0.8%). Among the reasons for donor rejection, mismatch between the donor’s blood group and that of the requested unit was the commonest (25.8%) followed by hypertension (22.9%) on examination. HBsAg seropositivity was the majority (0.5%) among the transfusion transmitted infections screened. Conclusion: Efforts should be made to direct all the donations towards voluntary non remunerated ones. Awareness among the general population about the need of blood donation, educating them about the criteria of acceptable donors and discussing the general myths and facts about donation process is also important.
Aim: To assess the demographic profile of blood donors and determine the frequency and causes for deferral. Study Design: Retrospective cross-sectional study. Place and Duration of Study: Department of Pathology, Blood Centre at Dr. SMCSI medical college, Karakonam, Trivandrum. January 2018 to September 2022. Methodology: This study was done to analyze the various causes of deferral and the profile of donors. 8064 donors from the study period were analyzed and their demographic profile was recorded. The deferred donors were analyzed according to their age, sex, type of donor, type of deferral and reasons for deferral. Results: 8064 donors came to our center for donation of which 7682 (95.3%) were males and 382 (4.7%) were females. Majority of blood donors belonged to age group 18-25 years (50.6%). Replacement donors accounted for 6596 donors (81.8%). Voluntary donors were only 940 (11.7%). 1541 (19.1%) donors were deferred from donating. Out of these, 1186(77%) were replacement donors, 198(12.8%) were voluntary donors and 160(10.2%) were family donors. The most frequent causes of temporary deferrals: Hypertension 314(20.2%), Hypotension 82(5.3%), low hemoglobin 110(7.1%), On medication 104(6.7%), Tattoo/ ear piercing/smoking/pan chewing 154(10%), previous recent illness/surgery 190(12.3%) and alcoholism 46(3%). Permanent deferrals were done for only 68 donors (0.7%). They included 21 high risk donors and 47 donors who were serology positive. Conclusion: Deferral pattern analysis can help the medical personnel in knowing the common causes of deferral and be more focused in screening. Determination of cause and rate donor deferral can help in preventing loss of precious blood and components.
We report the case of an 80 year old lady with multiple scalp swellings of 4 months duration. On further evaluation, the computerized tomography (CT) scan showed multiple well defined isodense to hyperdense soft tissue swellings on the left frontal region without any intracranial extension. A biopsy of the lesion was taken which on histopathological and immunohistochemical examination confirmed the diagnosis of epithelioid angiosarcoma. The patient was treated with adjuvant radiotherapy and on follow up has local recurrences at the same site six months after initial diagnosis. To conclude; epithelioid angiosarcoma is an aggressive tumour of elderly patients with local recurrences and poor prognosis.
Introduction: Skin appendageal tumors are wide spectrum of disorders that differentiate towards one or more adnexal structures. Objective: To determine the prevalence of skin appengeal tumours. Materials and methods: This is a record based cross sectional study from the Department of pathology, Dr SMCSI Medical College between 1 st January 2004 to 1 st November 2014 who were diagnosed with skin tumours by histopathology and these cases were reviewed classified and analysed according to the patient's age, gender, and localization. Results: 166 cases were studied during this study period, males 68 and females 98. Mean age of presentation in this study was 34 years. Tumours with follicular differentiation constituted the maximum, 81 cases (48.8%), followed by eccrine differentiation constituting 22 cases (13.25%): tumours with apocrine differentiation 21cases (12.66%) and sebaceous differentiation 9 cases (5.4%). One case each of sebaceous adenoma and sebaceous carcinoma were the only malignant tumours. Conclusion: Skin adnexal tumours are relatively uncommon and the incidence of benign skin adnexal tumours are more common compared to the malignant ones.
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