Study of complexing of polyacrylic acid with Cu2+ and Fe3+ ions

Tropsha, Ye.G.; Polinskii, A.S.; Yaroslavov, A. A.; Pshezhetskii, V.S.; Kabanov, V.A.

doi:10.1016/0032-3950(86)90321-7

Cited by 2 publications

(4 citation statements)

References 4 publications

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“…These data indicate that the metal ions are unevenly distributed between the protein molecules: some protein globules may sorb the maximal quantity of Cu 2+ ions, possible under given conditions, while the others remain practically unpopulated. Just this type of distribution was found previously at complexation of linear polyanionic and polycationic PE with Cu 2+ ions. , The PE−Cu 2+ complex exists as a chelate with carboxylate groups bound by copper ions. According to the literature 38-42 BSA has one specific binding site for Cu 2+ at the NH 2 -terminal tripeptide segment (Ala-Ala-His ...) involving the Asp α-NH 2 , His N(1) imidazole, two deprotonated peptide nitrogens (Ala NH and His NH), and the Asp COO - group.…”

Section: Resultssupporting

confidence: 77%

“…Just this type of distribution was found previously at complexation of linear polyanionic and polycationic PE with Cu 2+ ions. 9,36 The PE-Cu 2+ complex exists as a chelate with carboxylate groups bound by copper ions. According to the literature [38][39][40][41][42] BSA has one specific binding site for Cu 2+ at the NH 2 -terminal tripeptide segment (Ala-Ala-His ...) involving the Asp R-NH 2 , His N(1) imidazole, two deprotonated peptide nitrogens (Ala NH and His NH), and the Asp COOgroup.…”

Section: Resultsmentioning

confidence: 99%

“…PE − Cu 2+ and BSA − Cu 2+ Complexes. The formation of water-soluble polymer−metal complexes in mixtures of PAA−Cu 2+ and poly(NIPAAm−AA)-Cu 2+ were analyzed earlier by the titration shift method and measurements by HPLC, cyclic voltammetry, spectroscopy, equilibrium dialysis, and fast sedimentation methods. − It was shown that water-soluble and insoluble stable polyanion−Cu 2+ complexes are formed in the wide range of pH, and the solubility of polycomplexes depends on the metal/polymer ratios and pH of solutions.…”

Section: Resultsmentioning

confidence: 99%

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Fluorescence Study of Cu²⁺-Induced Interaction between Albumin and Anionic Polyelectrolytes

Filenko¹,

Demchenko²,

Mustafaeva³

et al. 2000

Biomacromolecules

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The Cu(2+)-induced complex formation of bovine serum albumin (BSA) with anionic polyelectrolytes (PEs) (polyacrylic acid (PAA), poly(N-isopropylacrylamide) [poly[NIPAAm]], and copolymers of N-isopropylacrylamide (NIPAAm) and acrylic acid) in aqueous solution was studied by a fluorescence technique and high-performance liquid chromatography analysis. The character of the interactions depends on the monomer composition (r = [COOH]/[NIPAAm]), [Cu(2+)]/[PE], and [BSA]/[PE] ratios and solution pH. Two types of ternary polycomplex (polymer + Cu(2+) + BSA) particles are formed depending on the monomer composition r of the copolymer. At r from 1/3 to 1/1, the protein molecules in the structure of ternary polycomplex particles are densely covered by the shell of a polymer coil and practically "fenced off" from the water environment. At r > or = 3/1 ternary polycomplex PAA-Cu(2+)-BSA particles have more friable structures in which protein molecules are practically exposed to the solution. At low polymer concentration, an intrapolymer ternary polycomplex is formed. This complex aggregates to an interpolymer species upon increase in polymer concentration. Fluorescence data indicate that in ternary complex polymer interacts through Cu(2+) ions with BSA preferentially at the site close to the location of "cleft" tryptophan residue. This leads to static quenching of this tryptophan fluorescence. Cu(2+)-induced complex formation is an equilibrium reaction.

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Section: Resultssupporting

confidence: 77%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Fluorescence Study of Cu²⁺-Induced Interaction between Albumin and Anionic Polyelectrolytes

Filenko¹,

Demchenko²,

Mustafaeva³

et al. 2000

Biomacromolecules

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“…This is similar to the effect of FeCl 3 on poly(acrylic acid). 15,22 Analysis of the product showed the metal ions to distribute unevenly between the macromolecules, forming an iron-rich fraction that precipitated and an iron-free fraction that stayed in solution. The crosslinking species has been shown to be FeCl 2ϩ using infrared spectroscopy 15 ; similarly, therefore, in the Fe(NO 3 ) 3 -poly(acrylic acid) adduct, the crosslinkers are likely to be Fe(NO 3 ) 2ϩ ions, rather that Fe 3ϩ ions.…”

mentioning

confidence: 99%

The effect of trivalent metal nitrates on the properties of dental cements made from poly(acrylic acid)

Nicholson

1998

J. Appl. Polym. Sci.

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Addition of either Al(NO 3 ) 3 or Fe(NO 3 ) 3 to zinc polycarboxylate and glass polyalkenoate dental cements has been shown to cause an acceleration to their setting reactions. In the case of Fe(NO 3 ) 3 , the reaction was so fast that cements could not be mixed, but Al(NO 3 ) 3 had a less severe effect, and cements containing various amounts of this additive were prepared. Their compressive strength at 24 h was lower than for the original cements, with zinc polycarboxylate being more affected than the glass polyalkenoate. Both cements are made from poly(acrylic acid), and infrared spectroscopy showed that both Al(NO 3 ) 3 and Fe(NO 3 ) 3 form adducts with this polymer, the interaction of aluminum with the polymer being significantly different from that of the iron (III) species. The binding by Al(NO 3 ) 3 was also shown to reduce the pH of a poly(acrylic acid) solution.

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Study of complexing of polyacrylic acid with Cu2+ and Fe3+ ions

Cited by 2 publications

References 4 publications

Fluorescence Study of Cu²⁺-Induced Interaction between Albumin and Anionic Polyelectrolytes

Fluorescence Study of Cu²⁺-Induced Interaction between Albumin and Anionic Polyelectrolytes

The effect of trivalent metal nitrates on the properties of dental cements made from poly(acrylic acid)

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Study of complexing of polyacrylic acid with Cu2+ and Fe3+ ions

Cited by 2 publications

References 4 publications

Fluorescence Study of Cu2+-Induced Interaction between Albumin and Anionic Polyelectrolytes

Fluorescence Study of Cu2+-Induced Interaction between Albumin and Anionic Polyelectrolytes

The effect of trivalent metal nitrates on the properties of dental cements made from poly(acrylic acid)

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Fluorescence Study of Cu²⁺-Induced Interaction between Albumin and Anionic Polyelectrolytes

Fluorescence Study of Cu²⁺-Induced Interaction between Albumin and Anionic Polyelectrolytes