Studies on wound healing properties of &lt;i&gt;Crateva religiosa&lt;/i&gt; leaf extract

Ajali, U; Km, Ezealisiji; Onuoha, E.C.

doi:10.4314/jophas.v7i4.63457

Cited by 4 publications

(3 citation statements)

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“…Rubefacient substances used on cysts include the ground leaves and bark (Kabore et al, 2015). The bark of the plant has been used to cure ailments like syphilis, jaundice, yellow fever, mycotic infections, and to hasten the healing of wounds, according to Ajali et al (2010), Adjabga et al (2017), andKumar et al (2020). The long list of successes recorded from the use of the extracts of the various tissues of the species in treatment of different ailments and hence, the need to make available large quantity of the plant materials, which can sustain biotechnological exploitation excited interest in selecting rooting of the stem cuttings which is an aspect of vegetative propagation for this study.…”

Section: Introductionmentioning

confidence: 99%

Effects of indole butyric acid and coconut liquid endosperm on rooting of Crateva adansonii stem

Nwankwo,

Ogwo,

Oti

et al. 2023

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Indole butyric acid (IBA) and coconut liquid endosperm (CLE), two rooting agents, were tested in three concentrations to see how they affected the rooting of Crateva adansonii DC stem cuttings. 300 mg/L, 200 mg/L, and 100 mg/L (IBA) of rooting material and 100%, 80%, and 60% of CLE were the concentrations that were assessed. This was done in three replications using completely randomized design (CRD). The setup, which lasted six months, was on exhibit in the Botanic Garden at the Department of Plant Science and Biotechnology, University of Nigeria, Nsukka. While control stem cuttings took the longest to start and finish bud break on the stem cuttings, higher concentrations of the rooting chemical substances, 300 mg/L IBA and 100 percent CLE respectively, influenced the shortest times (initial and final). The results showed that the control had the fewest buds that sprouted into leaves, whereas 300 mg/L IBA and 100 percent CLE had the highest percentage of buds that turned into leaves on the stem cuttings. Regardless of the treatment concentrations utilized, a thin callus formed on the stem cuttings. Observations on rooting revealed that not all callused stem cuttings subsequently took root. IBA and CLE were applied to stem cuttings in various concentrations, and the results were seedlings with lateral and feeding roots. The maximum percentage of rooting response was seen in stem cuttings treated with 300 mg/L IBA and 100 percent CLE, respectively, while the control did not root. The findings of measuring the aerial and sub aerial growth characteristics of seedlings revealed that 300 mg/L IBA and 100 percent CLE had a greater impact on the development of higher values of the growth parameters examined than cuttings treated with lower concentrations of the two rooting agents. Based on the findings of this study, it is possible to draw the conclusion that C. adansonii can be multiplied vegetatively by using rooting agents to help stem cuttings take root. It is recommended that more research be done using rooting medium with a higher concentration and rooting agents like auxins at different concentrations.

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Section: Introductionmentioning

confidence: 99%

Effects of indole butyric acid and coconut liquid endosperm on rooting of Crateva adansonii stem

Nwankwo,

Ogwo,

Oti

et al. 2023

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“…ssp. adansonii is also used to treat mycotic diseases and also to accelerate the process of wound healing (Sabuj et al, 2008;Ajali et al, 2010). Populations use the leaves and bark of this tree to treat jaundice, eczema and rabies (Ganesan et al, 2009).…”

Section: Introductionmentioning

confidence: 99%

Antihypertensive effect of extracts from <i>Crateva adansonii</i> DC.ssp. <i>adansonii</i> in the Wistar rats

Adjagba¹,

Awede²,

Osseni³

et al. 2018

Int. J. Bio. Chem. Sci

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Crateva adansonii DC.ssp. adansonii (CA) is a medicinal plant used in traditional medicine to treat various diseases including hypertension. The main objective of this study was to assess the effect of the plant on high blood pressure. The crude aqueous extract of CA has undergone a liquid-liquid fractionation with increasing polarity solvents. The phytochemical analysis of the extracts was carried out by using the thin layer chromatography method. The pharmacological effect was evaluated in Wistar rats made hypertensive by administering the N (ω)-Nitro-L-Arginine-Methyl Ester (L-NAME). The crude extract was administered at 500 mg / kg (b/w) and the fractions (aqueous, butanol, dichloromethane and ethyl acetate) at 30 mg / kg (b/w). Blood pressure was measured by a non-invasive caudal arterial measurement method. Flavonoids, coumarins terpens, anthracens were detected diversely distributed either the crude extract or in the fractions. The crude aqueous extract induced a significant decrease in blood pressure from 155.6 ± 9.28 mm Hg to 106.00 ± 8.27 mm Hg. On the other hand, ethyl acetate and dichloromethane fractions exerted the highest effects among the fractions by reducing the blood pressure respectively from 139.8 ± 6.83 mmHg to 98.6 ± 8.38 mmHg and to 106.6 ± 6.80 mmHg. The results obtained justify the traditional use of the leaves of CA in the treatment of high blood pressure.

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“…The plant has been studied for suppressing various immune factors (Bani et al, 2006); Antimycotic potential (Sahoo et al, 2008); Ant mutagenic activity (Chichioco-Hernandez et al, 2009); Wound healing (Ajali et al, 2010); Anti-inflammatory activity (Abdullahi et al, 2012); Antimicrobial activity (Agboke et al, 2011); Antioxidant activity (Pandey et al, 2013). The profiling of Secondary metabolites and the antimicrobial activity on understudy microorganisms was checked for the first time.…”

Section: Introductionmentioning

confidence: 99%

Profiling of secondary metabolites and antimicrobial activity of Crateva religiosa G. Forst. Bark – A rare medicinal plant of Maharashtra India

2017

Int. J. Biosci.

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In the present study Profiling of Secondary metabolites and Antimicrobial activity of Stem Bark of Crateva religiosa was carried out for validating the ethno medicinal claims. Stem Bark of this plant was analyzed for Physiochemical study, Organoleptic study and Fluorescent analysis. Qualitative and Quantitative analysis of major secondary metabolites was also carried out using standard procedures. Stem bark was extracted successively using Chloroform, Dichloromethane and 50% Ethanol as solvents which were analyzed by Gas Chromatography -Mass Spectrometry (GC-MS) method to separate and identify the individual compounds in extracts. Antimicrobial activities of all three extracts of understudy part was tested against 4 pathogenic bacterial strains and two fungal strains. The results of antimicrobial activity were compared with the results of standard antibiotics. The physiochemical results determined that percentage of moisture content 6.70 ± 0.59, Ash content 22.18 ± 1.17, Highest Extractive values 15.85 ± 0.21 were found in 50% Ethanol extracts. The qualitative analysis showed presence of various secondary metabolites among which major groups were quantified. By GC-MS analysis the different phyto compounds were identified among which 9 were secondary metabolites and were placed as profile of secondary metabolite in Stem bark. All three solvent extracts showed significant activity against bacterial strains while as chloroform extracts were inactive against fungal strains at 10mg/ml concentration. The results suggest that this plant has vast variety of photochemical which can be used as effective remedy for various ailments and drug formulations in future. The ethnic claims of this plant were also verified by the present study.

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Studies on wound healing properties of <i>Crateva religiosa</i> leaf extract

Cited by 4 publications

References 0 publications

Effects of indole butyric acid and coconut liquid endosperm on rooting of Crateva adansonii stem

Effects of indole butyric acid and coconut liquid endosperm on rooting of Crateva adansonii stem

Antihypertensive effect of extracts from <i>Crateva adansonii</i> DC.ssp. <i>adansonii</i> in the Wistar rats

Profiling of secondary metabolites and antimicrobial activity of Crateva religiosa G. Forst. Bark – A rare medicinal plant of Maharashtra India

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