Studies on the Vitamin C Metabolism of Four Preschool Children1

A Study of Ascorbic Acid Metabolism of Adolescent Children

“…The 31 mg intake found by Hathaway and Meyer (1941) to maintain tissue saturation in four preschool children was equivalent to 1.5 to 1.8 mg/kg for these children. The five children from 7 to 12 years of age studied by Roberts and Roberts (1942) required from 1.7 to 2.4 mg/kg to maintain tissue saturation.…”

“…The studies reviewed in the introduction include the requirements of many adults for saturation with ascorbic acid. Although some investigators have questioned the existence of any relationship between ascorbic acid requirement and body weight (Hathaway and Meyer 1941;Ralli et al 1939), many workers have reported their results in mg per kg of body weight. Of 30 adults whose requirements for tissue saturation were studied by Belser, Hauck, and Storvick (1939) ; Ralli et al (1939) ; Todhunter and Robbins (1940) ; Fincke and Landquist (1942) ; Storvick and Hauck (1942) ; and Kline and Eheart (1944), the estimated requirements of 24 fell between 13 and 1.8 mg/kg.…”

Recommended Dietary Allowances

“…Significant data and additional citations of the literature will be found in the recent references given, dealing primarily with maternal and infant feeding (86-90) requirements of children (91)(92)(93)(94), requirements of adults (95)(96)(97)(98)(99)(100)(101)(102)(103), distribution in human tissues (104), effects upon tooth structure (105)(106)(107), and the enzyme contents of wounds during healing (108).…”

Recommended dietary allowances

“…Significant data and additional citations of the literature will be found in the recent references given, dealing primarily with maternal and infant feeding (86)(87)(88)(89)(90) requirements of children (91)(92)(93)(94), requirements of adults (95)(96)(97)(98)(99)(100)(101)(102)(103), distribution in human tissues (104), effects upon tooth structure (105)(106)(107), and the enzyme contents of wounds during healing (108).…”