1975
DOI: 10.1016/0009-8981(75)90105-9
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Studies on the stability of pancreatic enzymes in duodenal fluid to storage temperature and pH

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1976
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Cited by 20 publications
(3 citation statements)
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“…Amylase and trypsin activities decreased quickly in contaminated pancreatic juice. LEGG and SPENCER (1975) studied the stability of pancreatic enzymes in human duodenal fluid to storage temperature and pH. They found that the activity of amylase, trypsin and lipase remained relatively constant over a 4 week period when stored at -20°C.…”
Section: Evaluation Of Methods To Analyze Pancreatic Enzyme Activitiesmentioning
confidence: 99%
“…Amylase and trypsin activities decreased quickly in contaminated pancreatic juice. LEGG and SPENCER (1975) studied the stability of pancreatic enzymes in human duodenal fluid to storage temperature and pH. They found that the activity of amylase, trypsin and lipase remained relatively constant over a 4 week period when stored at -20°C.…”
Section: Evaluation Of Methods To Analyze Pancreatic Enzyme Activitiesmentioning
confidence: 99%
“…In 1975, Legg and Spencer documented stability of 70% in trypsin stored in duodenal juice at room temperature for 4 days. 62 In a 1988 paper, Moskvichyov et al 63 demonstrated that trypsin is stable, though inactive, in acid, reverting to its active form when in an alkaline pH.…”
Section: Parenteral Versus Oral Enzyme Administrationmentioning
confidence: 99%
“…Панкреатичні ферменти є чутливими до рН оптимум при майже 7 [21]. Вони піддаються денатурації у кислому се редовищі, тому препарати випускають у кислотостійких обо лонках, які повинні бути цілісними при кислому рН шлунка і швидко розчинятися при потраплянні до 12 палої кишки [17,18].…”
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