Studies on the serological relationships between avian pox, sheep pox, goat pox and vaccinia viruses

Abstract

SUMMARYBy using neutralization, complement fixation and immunogel-diffusion tests, it has been demonstrated that cross-reactions occur between various avian pox viruses and between sheep pox and goat pox viruses. No such reactions were demonstrated between avian pox viruses and vaccinia virus or between avian pox and sheep pox and goat pox viruses. Furthermore, no serological relationship was demonstrable between vaccinia virus and sheep pox and goat pox viruses.

A Short Note on Sheep Pox Virus Soluble Antigens Studied by Immunodiffusion

“…These results are in general agreement with studies on vaccinia, cow pox and pig pox viruses (12,9,20,5). Some authors (1, 19, l l ) , however, demonstrated as many as 17-20 bands in vaccinia and rabbit pox viruses, but similar studies on goat pox and sheep pox viruses indicated fewer bands (2,17,18,10). The increased number of precipitation bands in the present study may be attributed to two factors; the use of concentrated soluble antigens along with Freund's complete adjuvant for raising hyperimmune serum and diffusion of the reactants at 4 OC.…”

“…A number of antigens have been reported in sheep pox virus infected tissues using the immunodiffusion technique ( 2 , 14,15,16,17,18). It was 'demonstrated in the above studies that sheep pox virus reacted with its homologous antisera and produced one to five precipitation bands.…”

Studies on the Major Common Precipitating Antigen of Capripoxvirus

“…The agar gel immunodiffusion test (AGID) has been used to demonstrate the serological relationship between members of the Orthopoxvirus group (Esposito et al, 1977), the Avipoxvirus group (Uppal & Nilakantan, 1970) and the Capripoxvirus group (Sharma & Dhanda, 1971a;Pandey & Singh, 1972). Sheep and goats that have recovered from capripox infection develop precipitating antibodies that can be detected between 10 and 50 days postinfection (Lefevre, 1983).…”

Characterization of a Cell Culture Adapted Goat Pox Virus1

“…In both species the pox diseases severely affect the production of meat, milk, fibre (wool and hair), hide and offspring. Views on the degree of relatedness between I 544 TALHOUK and EL-ZEIN the two viruses have been conflicting: absence of an antigenic relationship between sheep pox virus (SPV) and goat pox virus (GPV) (3) as well as the presence of partial (14,15,16,18) and complete (2, 4, 6) antigenic cross-reactivity have been reported. Pathogenic species-specific viruses have been described (9,17).…”