Studies on the Nature of Antihemophilic Factor (Factor VIII)

Bennett, Bruce; Forman, Walter B.; Ratnoff, Oscar D.

doi:10.1172/jci107404

Cited by 38 publications

(4 citation statements)

References 9 publications

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“…Both VIII-Ac and VIII-Ag appear together during purification steps (1 6,17) and the antibody produced by injection of purified factor VIII protein forms a precipitin line with factor VIII-containing material on immunoelectrophoresis and simultaneously neutralizes factor VIII clot-promoting activity (1 3, 18). Therefore, it has been suggested that both VIII-Ac and VIII-Ag reside on the same molecule (13,18,19).…”

Section: Discussionmentioning

confidence: 99%

In vivo dissociation of factor vii (ahf) activity and factor viii‐related antigen in von willebrand's disease

Lian

Deykin

1976

American J Hematol

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Using monospecific rabbit antihuman factor VIII antiserum, we have examined the amounts of factor VIII-related antigen and compared these to the levels of factor VIII procoagulant activity in normal subjects and patients with von Willebrand's disease. We have observed that even without transfusion all nine probands with von Willebrand's disease and 20 of their 34 relatives possessed a significantly elevated factor VIII activity/factor VIII-related antigen ratio when compared to that of 55 normal subjects. It is suggested that an elevated factor VIII activity/factor VIII-related antigen ratio may be used for detection of the carriers of von Willebrand's disease.

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Section: Discussionmentioning

confidence: 99%

In vivo dissociation of factor vii (ahf) activity and factor viii‐related antigen in von willebrand's disease

Lian

Deykin

1976

American J Hematol

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“…Other studies of the subunit size of factor VIII have varied from 22 000-300 OO0. [3][4][5][6][7] These studies of human factor VIII suggest that large repetitive subunits identical in size form this macromolecule by disulfide bonds.…”

mentioning

confidence: 85%

Theoretical Approach to Molecular Biology of Factor Viii: Heterogeneity of the Molecule

Gralnick

Marchesi

Coller

1975

Annals of the New York Academy of Sciences

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“…56 For example, Jane Bennett, in her work on 'vibrant matter,' challenges the binding of 'subjectivity' to the fantasy of 'human uniqueness' 57 and the 'fantasy that "we" are really in charge of those "its"'. 58 Bennett characterizes matter as an 'actant', 59 challenging the idea that objects are opposite to subjects through a focus on 'thingpower'. 60 Bennett notes that humans are part of a shared, 'vital materiality'.…”

Section: Posthuman Theories Of New Materialism and Ielmentioning

confidence: 99%

Posthuman international law and the rights of nature

Jones

2021

JHRE

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Both posthuman theory and the rights of nature (RoN) movement have the potential to challenge the anthropocentrism of international environmental law (IEL). Scholars have begun to document the transformative shifts that could occur through the application of posthuman legal theory to IEL, but these theories have yet to be applied to law in practice. On the other hand, RoN have been applied in domestic law but hardly in international law, while the question of what RoN includes and excludes remains contested. This article brings posthuman theory and RoN together, reflecting on how posthuman legal theory can contribute to the framing of RoN, with a focus on challenging the anthropocentrism of IEL. The article argues, first, that the next step for posthuman legal theory will be its application to existing law. Noting convergences between posthuman legal theory and the rights of nature (RoN), the article contends that those seeking to apply posthuman legal theory might find some interesting alliances by turning to RoN. Second, it is argued that using posthuman theory to frame RoN could help to ensure that RoN live up to their transformative potential.

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Studies on the Nature of Antihemophilic Factor (Factor VIII)

Cited by 38 publications

References 9 publications

In vivo dissociation of factor vii (ahf) activity and factor viii‐related antigen in von willebrand's disease

In vivo dissociation of factor vii (ahf) activity and factor viii‐related antigen in von willebrand's disease

Theoretical Approach to Molecular Biology of Factor Viii: Heterogeneity of the Molecule

Posthuman international law and the rights of nature

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