Studies on the determination of inorganic anions by capillary electrophoresis

Benz, Nancy J.; Fritz, James S.

doi:10.1016/0021-9673(94)80271-8

Cited by 53 publications

(27 citation statements)

References 24 publications

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“…Benz and Fritz [36] used butanol in conjunction with Q' to reverse the EOF. Under typical experimental conditions, a concentration of greater than 0.25 mM Q' is required in the carrier electrolyte to reverse the direction of the EOF.…”

Section: Electroosmotic Flow Modifiersmentioning

confidence: 99%

Separation of ions in acidic solution by capillary electrophoresis

Thornton

1997

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Section: Electroosmotic Flow Modifiersmentioning

confidence: 99%

Separation of ions in acidic solution by capillary electrophoresis

Thornton

1997

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“…On the other hand, the indirect UV detection appears more attractive due to its universality. The chromophore commonly introduced into the electrolyte to generate the background signal is the chromate [12,[16][17][18]21,27,29,31,37]. However the utilization of dich ro m ate [11,30,34], p h t a l ate [7,14,20], py ro m e l l i t i c acid [20,26,27] or polysulfonated naphtalenes [8] can be also noted.…”

Section: Introductionmentioning

confidence: 99%

“…For instance OFM Anion -BT [16][17][18]32,35], cetyltrimethylammonium (CTAB) [21][22][23][24][25]36,37], hexamethonium [20,27,28,34] or trimethyltetradecylammonium (TTAB) [27,[29][30][31]33,[36][37][38] can be noted.…”

Section: Introductionmentioning

confidence: 99%

Optimization of the indirect fluorimetric detection for the simultaneous analysis of inorganic anions and polycharged organic anions by capillary electrophoresis

1998

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“…Complex mixtures of analytes can be resolved and recorded as sharp peaks due to the lower risk of zone broadening. In its diverse modes of operation (capillary free zone electrophoresis (CZE) [3][4][5], micellar electrokinetic chromatography (MEKC) [6][7][8][9][10], capillary gel electrophoresis (CGE) [11][12][13][14], capillary isotacophoresis (CTTP) [15][16][17], capillary isoelectric focusing (CIEF) [18][19][20], and capillary electrochromatography (CEC) [21][22][23]), CE can be applied to analyze a wide variety of analytes ranging from low molecular weight analytes such as inorganic anions [24][25][26][27][28], metal cations [29][30][31][32], drugs [33][34][35] to larger molecules such as oligosaccharides [36][37][38][39][40], peptides [11,[41][42][43], proteins [5,[44][45][46], DNA [46][47][48][49]…”

Section: Capillary Electrophoresismentioning

confidence: 99%

“…In the CE separation of inorganic anions and small organic anions, Benz and Fritz [35] found that reversal of the direction of electroosmotic flow by a quaternary ammonium salt (Q"^) similar to CTAB could be achieved at much lower concentrations (<0.1 mM) if about 5% n-butanol was added to the electrolyte. They explained that use of such a low concentration of Q"^ was possible because both butanol and were adsorbed on the capillary surface.…”

Section: N-biitanol Additive Effectmentioning

confidence: 99%

Capillary electrophoresis separation of neutral organic compounds, pharmaceutical drugs, proteins and peptides, enantiomers and anions

Ding

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This manuscript has been reproduced from the microfilm master. UMI films the t»ct directly from the original or copy submitted. Thus, some thesis and dissertation copies are in typewriter face, while others may be from any type of computer printer.The quality of this reproduction is dependent upon the quality of the copy submitted. Broken or indistinct print, colored or poor quality illustrations and photographs, print bleedthrough, substandard margins, and improper alignment can adversely affect reproduction.In the unlikely event that the author did not send UMI a complete manuscript and there are missing pages, these will be noted. Also, if unauthorized copyright material had to be removed, a note will indicate the deletion.Oversize materials (e.g., maps, drawings, charts) are reproduced by sectioning the original, beginning at the upper left-hand comer and continuing from left to right in equal sections with small overlaps. Each original is also photographed in one e7q)osure and is included in reduced form at the back of the book.Photographs included in the original manuscript have been reproduced xerographically in this copy. Higher quality 6" x 9" black and white photographic prints are available for any photographs or illustrations appearing in this copy for an additional charge. Contact UMI directly to order. The effect of adding this new surfactant to the acidic electrolyte was also investigated. UMIWorking at acidic condition at pH 2.4 has the advantage that electroosmotic flow is virtually eliminated. Neutral compounds are dragged by their association with the surfactant, moving as the same direction as the surfactant, resulting in fast separations. Basic compounds are also investigated under the same conditions. Excellent resolution of a mixture of 19 polyaromatic hydrocarbons was obtained in only 20 min.Incorporation of cetyltrimethylammonium bromide in the electrolyte is shown to dynamically coat the capillary and reverse electroosmotic flow. The coating prevents basic proteins and peptides adsorption into the capillary wall, resulting in high separation efficiencies. A systematic study of experimental parameters demonstrated the importance of selecting a suitable buffer and an appropriate pH.Gliral recogmtion mechanism is smdied using several novel synthetic surfactants as chiral selectors, which are made from amino acids reacting with al&yl chloroformates. It was found that enantiomeric resolution can be readily manipulated by varying the alkyl groups (different chain lengths), amino acids and surfactant concentrations. Sulfonated Bcyclodextrin is also employed as a chiral selector to compare chiral selectivity with these synthetic surfactants. A duo-chiral selectors system is further investigated for the possibility of eliminating some tedious steps in chiral compounds method development.A satisfactory separation of both inorganic and organic anions is obtained using electrolyte solutions as high as 5 M sodium chloride using direct photometric detection. The temperature inside the capillary that ...

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Studies on the determination of inorganic anions by capillary electrophoresis

Cited by 53 publications

References 24 publications

Separation of ions in acidic solution by capillary electrophoresis

Separation of ions in acidic solution by capillary electrophoresis

Optimization of the indirect fluorimetric detection for the simultaneous analysis of inorganic anions and polycharged organic anions by capillary electrophoresis

Capillary electrophoresis separation of neutral organic compounds, pharmaceutical drugs, proteins and peptides, enantiomers and anions

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