Studies on the cardiac physiology of Onychophora and Chilopoda

Hertel, Wieland; Wirkner, Christian S.; Pass, Günther

doi:10.1016/s1095-6433(02)00192-7

Cited by 20 publications

(11 citation statements)

References 23 publications

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“…[44] demonstrated a significant in vitro inhibition of cytosolic CA by Ag + , Cd 2+ , Cu 2+ and Zn 2+ in the gills of the crabs Callinectes sapidus and Carcinus maenas. The inhibition was species-specific with a binding affinity for the metals one thousand times weaker in C. maenas with respect to C .…”

Section: Carbonic Anhydrase and Heavy Metalsmentioning

confidence: 99%

Carbonic Anhydrase as Pollution Biomarker: An Ancient Enzyme with a New Use

Lionetto

Caricato

Giordano

et al. 2012

IJERPH

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The measurement of cellular and sub-cellular responses to chemical contaminants (referred to as biomarkers) in living organisms represents a recent tool in environmental monitoring. The review focuses on carbonic anhydrase, a ubiquitous metalloenzyme which plays key roles in a wide variety of physiological processes involving CO2 and HCO3−. In the last decade a number of studies have demonstrated the sensitivity of this enzyme to pollutants such as heavy metals and organic chemicals in both humans and wildlife. The review analyses these studies and discusses the potentiality of this enzyme as novel biomarker in environmental monitoring and assessment.

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Section: Carbonic Anhydrase and Heavy Metalsmentioning

confidence: 99%

Carbonic Anhydrase as Pollution Biomarker: An Ancient Enzyme with a New Use

Lionetto

Caricato

Giordano

et al. 2012

IJERPH

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“…Most deficiencies of peristaltic design can be summed up by stating that peristaltic pumps lack effective coordination between the fluid that is entering the contractile region and the fluid that is leaving it [51]. This, of course, does not mean that peristaltic pumps can not be improved, or that backflow cannot be exploited to the animals advantage [85,88]. Backflow in arthropod peristaltic pumps is Cell.…”

Section: The Limits Of Peristaltic Vesselsmentioning

confidence: 99%

“…Although sufficiently 728 J. Xavier-Neto et al Evolutionary origins of pumping organs sophisticated on its own, the arthropod dorsal vessel was initially designed as a peristaltic organ, not as a chambered pump [87,88]. As discussed above, its blueprints reflect a fundamentally different approach to the problem of fluid propulsion than the one chosen for vertebrates and molluscs in their chambered hearts.…”

Section: Back To Homologymentioning

confidence: 99%

Cardiovascular development: towards biomedical applicability

Xavier‐Neto¹,

Castro

Sampaio

et al. 2007

Cell. Mol. Life Sci.

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Research in animal models established that tinman, a key gene in Drosophila dorsal vessel development, is an orthologue of Nkx2-5, a key gene in vertebrate cardiac development. Similarities between the arthropod dorsal vessel and vertebrate hearts are interpreted in light of concepts such as homology or convergence. We discuss this controversy in the context of the evolution of animal circulatory pumps and propose the distinction between peristaltic and chambered pumps as a fundamental parameter for evolutionary comparisons between bilaterian pumps. Neither homology nor convergence is satisfactory to explain the origins of hearts and pumping organs. Instead, we propose that animal pumps derive from parallel improvements of an ancestral, peristaltic design represented by a layer of myocytes at the external walls of primitive vessels. This paradigm unifies disparate views, impacts our understanding of bilaterian evolution and may be helpful to interpret similarities between pumping organs of phylogenetically relevant species and emerging models.

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“…Two types of recurrent electrical activities (perhaps not APs) of myocardial fibers are distinguished in Arthropoda. In Scolopendra cingulata and Lithobius forficatus , this rhythm was considered as myogenic, however, the additional oscillations at their plateau phase as neurogenic (Hertel, Wirkner, & Pass, ). In Peripatopsis , no plateau and corresponding oscillations were observed, and because the activity resembled those of pacemaker‐like potentials, they were concluded to be myogenic (Hertel et al, ).…”

Section: Introductionmentioning

confidence: 99%

“…TTX obliterates the cardiac electrical activity of S. cingulata , but at “heroic doses” of 300 μM (Gibson & Lang, ; Hertel et al, ). Interestingly, this obliteration is short term, because the rhythmicity is resumed after 25 min albeit the absence of plateau phase (Hertel et al, ). However, it is not clear whether TTX was applied only for 1 min or it was present up to 25 min.…”

Section: Introductionmentioning

confidence: 99%

Limulus and heart rhythm

et al. 2018

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Great interest in the comparative physiology of hearts and their functions in Animalia has emerged with classic papers on Limulus polyphemus and mollusks. The recurrent cardiac activity-heart rate-is the most important physiological parameter and when present the kardia (Greek) is vital to the development of entire organs of the organisms in the animal kingdom. Extensive studies devoted to the regulation of cardiac rhythm in invertebrates have revealed that the basics of heart physiology are comparable to mammals. The hearts of invertebrates also beat spontaneously and are supplied with regulatory nerves: either excitatory or inhibitory or both. The distinct nerves and the source of excitation/inhibition at the level of single neurons are described for many invertebrate genera. The vertebrates and a majority of invertebrates have myogenic hearts, whereas the horseshoe crab L. polyphemus and a few other animals have a neurogenic cardiac rhythm. Nevertheless, the myogenic nature of heartbeat is precursor, because the contraction of native and stem-cellderived cardiomyocytes does occur in the absence of any neural elements. Even in L. polyphemus, the heart rhythm is myogenic at embryonic stages.

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Studies on the cardiac physiology of Onychophora and Chilopoda

Cited by 20 publications

References 23 publications

Carbonic Anhydrase as Pollution Biomarker: An Ancient Enzyme with a New Use

Carbonic Anhydrase as Pollution Biomarker: An Ancient Enzyme with a New Use

Cardiovascular development: towards biomedical applicability

Limulus and heart rhythm

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