Studies on plant growth‐regulating substances: XXXII. Chlorosubstituted α‐hydroxy‐and α‐methoxy‐phenylacetic acids

Abstract

S U M M A R YThe plant growth-regulating activities of all the mono-and di-chlorosubstituted a-hydroxy-phenylacetic (mandelic) acids and their methoxy derivatives have been determined in the wheat coleoptile cylinder, pea segment and pea curvature tests. I n general, chloro-substituted a-hydroxy acids were less active in all three tests than the corresponding a-methoxy acids. The a-methoxy compounds and the dichloromandelic acids were more active in pea than in wheat tissues.These results are discussed in relation to the plant growth-regulating activities of the corresponding phenylacetic and phenoxyacetic acids.

A review on Arthrobacter sp. lipase: A versatile biocatalyst for the kinetic resolution to access enantiomerically pure/enriched compounds

“…These are the precursors of α‐methoxy aryl acetic acids which are reported to be utilized as chiral auxiliaries in Diels‐Alder reactions 100 and for the determination of absolute configuration of secondary alcohols, amines and sulfoxides by 1 H NMR 101 . α‐Alkoxyaryl acetic acids also behave as plant growth regulators, 102 calcium antagonists, 103 and also as apoptosis inhibitors 104 . Due to numerous biological and pharmacological properties of these molecules, a large number of chemical/chemoenzymatic methods are available in the literature for their synthesis in enantiomerically pure form 105–108 .…”