Studies on Maturity in Newborn Infants

Finnström, Orvar

doi:10.1111/j.1651-2227.1972.tb15899.x

Cited by 59 publications

(5 citation statements)

References 11 publications

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“…Seven (7) physical parameters which are scalp hair, skin opacity, length of fingernails, breast size, nipple formation, ear cartilage and plantar skin creases were used. This tool is not only easy to use but is also sensitive with an accuracy of +/− 2 weeks when administered within 24 h of birth [ 8 , 9 ]. To limit observer bias, gestational assessment of all babies was done by only one research assistant trained by the principal investigator and aided by a printed pictorial scoring chart.…”

Section: Methodsmentioning

confidence: 99%

Prevalence and factors associated with preterm birth at kenyatta national hospital

Wagura

Wasunna

Laving

et al. 2018

BMC Pregnancy Childbirth

160

127

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BackgroundThe World Health Organization estimates the prevalence of preterm birth to be 5–18% across 184 countries of the world. Statistics from countries with reliable data show that preterm birth is on the rise. About a third of neonatal deaths are directly attributed to prematurity and this has hindered the achievement of Millennium Development Goal-4 target. Locally, few studies have looked at the prevalence of preterm delivery and factors associated with it. This study determined the prevalence of preterm birth and the factors associated with preterm delivery at Kenyatta National Hospital in Nairobi, Kenya.MethodsA cross-sectional descriptive study was conducted at the maternity unit of Kenyatta National Hospital in Nairobi, Kenya in December 2013. A total of 322 mothers who met the eligibility criteria and their babies were enrolled into the study. Mothers were interviewed using a standard pretested questionnaire and additional data extracted from medical records. The mothers’ nutritional status was assessed using mid-upper arm circumference measured on the left. Gestational age was assessed clinically using the Finnstrom Score.ResultsThe prevalence of preterm birth was found to be 18.3%. Maternal age, parity, previous preterm birth, multiple gestation, pregnancy induced hypertension, antepartum hemorrhage, prolonged prelabor rupture of membranes and urinary tract infections were significantly associated with preterm birth (p = < 0.05) although maternal age less < 20 years appeared to be protective. Only pregnancy induced hypertension, antepartum hemorrhage and prolonged prelabor rupture of membranes remained significant after controlling for confounders. Marital status, level of education, smoking, alcohol use, antenatal clinic attendance, Human Immunodeficiency Virus status, anemia, maternal middle upper arm circumference and interpregnancy interval were not associated with preterm birth.ConclusionsThe prevalence of preterm birth in Kenyatta National Hospital was 18.3%. Maternal age ≤ 20 years, parity > 4, twin gestation, maternal urinary tract infections, pregnancy induced hypertension, antepartum hemorrhage and prolonged prelabor rupture of membranes were significantly associated with preterm birth. The latter 3 were independent determinants of preterm birth. At-risk mothers should receive intensified antenatal care to mitigate preterm birth.

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Section: Methodsmentioning

confidence: 99%

Prevalence and factors associated with preterm birth at kenyatta national hospital

Wagura

Wasunna

Laving

et al. 2018

BMC Pregnancy Childbirth

160

127

View full text Add to dashboard Cite

show abstract

“…Gestational age was determined on the basis of the last menstruation, early pregnancy ultrasound findings, and the Finnstrom maturity score for newborn infants. 15 Growth curves for identification of intrauterine growth retardation were taken from Roemer and colleagues. 16 Perinatal asphyxia was defined as a five-minute Apgar score less than 7 or as a severe acidosis (umbilical artery pH less than 7.10).…”

Section: Methodsmentioning

confidence: 99%

Maternal Hemolysis, Elevated Liver Enzymes, Low Platelet Count, and Neonatal Outcome

Harms¹,

Rath²,

Herting³

et al. 1995

Amer J Perinatol

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Pregnancies complicated by the syndrome of hemolysis, elevated liver enzymes, and low platelet count (HELLP) have been associated with both a poor maternal and a poor neonatal outcome in several publications. Because many studies were small and gave only scant information regarding the infants, we analyzed the clinical course of 89 neonates born to mothers with the HELLP syndrome. Ninety-eight percent of the neonates were born by cesarean section. Infants with a maternal HELLP syndrome were often small for gestational age (39%). The incidence of perinatal asphyxia was found to be 5.6%. Additionally, the affected very low birthweight (VLBW) infants had relatively high incidences of leukopenia (21%), neutropenia (33%), and thrombocytopenia (33%). Initially, 54% of the LBW infants were found to have normoblasts and 25% erythrocytosis. The incidence of these changes in blood cell count increased with decreasing birthweight. Nosocomial infections occurred more often in infants with a reduced neutrophil count. The overall mortality rate was 56 per 1000. Comparing the statistics of the VLBW infants with a maternal HELLP syndrome (n = 32) to all infants with a birthweight less than 1500 g (n = 521) during the investigational period, we found a similar mortality rate (9.3% and 8.4%, respectively). The pulmonary morbidity was also similar. The incidence of intracranial hemorrhage in VLBW infants with a maternal HELLP syndrome was lower (12.5% versus 18.2%) and of necrotizing enterocolitis was higher (6.2% versus 1.9%).

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“…The gestational age was recorded, taking into account information from mother and scored according to Finstrom. 9 Ethical considerations. According to a prophylactic treatment schedule routinely applied in the Neonatal Department, all patients would have recieved kanamycin.…”

Section: Methodsmentioning

confidence: 99%

Kinetics and dose calculations of amikacin in the newborn

Sardemann

Colding

Hendel

et al. 1976

Clin Pharma and Therapeutics

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The pharmacokinetics of a new aminoglycoside, amikacin, was evaluated in 37 infants between 1 and 34 days old. Fifteen were below 2,500 gm in weight. Initial studies, including intravenous infusion in some of the infants, indicated that the disposition of amikacin was best described by a 2 compartment model. The absorption was evaluated in 8 of the infants after intramuscular injection of 7.5 mg amikacin per kilogram of body weight. The absorption rate, estimated by the tmax, was significantly faster than reported in adults. The total body clearance and apparent volume of distribution were studied in 22 infants after the same dose of amikacin intramuscularly. The body clearance expressed in relation to body surface or body weight was significantly less than in adults and correlated with the postnatal age. No correlation could be demonstrated between clearance and gestational age or birth weight. The volume of distribution per kilogram was significantly greater than in adults. On the basis of the derived kinetic parameters, a dose schedule is presented. In 5 children there was a reasonable agreement between the measured and predicted serum levels.

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Studies on Maturity in Newborn Infants

Cited by 59 publications

References 11 publications

Prevalence and factors associated with preterm birth at kenyatta national hospital

Prevalence and factors associated with preterm birth at kenyatta national hospital

Maternal Hemolysis, Elevated Liver Enzymes, Low Platelet Count, and Neonatal Outcome

Kinetics and dose calculations of amikacin in the newborn

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