“…Iron-based catalysis has received much attention because of its natural abundance, low cost and environmentally friendly nature (Scheme 1b): 11 Xiao and coworkers reported Fe(OTf) 2 with a PyBisulidine ligand with low conversion with 1,1′-oxidi-isochromans as the byproducts; 11 a in 2017, Shen et al . successfully applied Fe(NO 3 ) 3 ·9H 2 O with KPF 6 for the aerobic oxidation of isochromans in MeCN at 80 °C; 11 b later, this transformation was also realized at 80 °C by Feng and He via the incorporation of dppf with disulfide; 11 c herein, based on our early reports with Fe(NO 3 ) 3 ·9H 2 O catalysis, 11 d ,12 we wish to report our recent observation that with the help of 4-OH-TEMPO, the Fe(NO 3 ) 3 ·9H 2 O catalyzed aerobic oxidation of isochromans could be realized in high yields under very mild conditions of rt (Scheme 1c).…”