Studies on biosynthesis of carotenoids in Neurospora crassa

The photoregulation of carotenoid biosynthesis in Aspergillus giganteus mut. alba

“…The reason for this anomaly is unknown, especially as the same strain and culture medium was used in both studies. No other carotenes were detected during the photoinduction experiment (Figures 3:3 and 3:4), whereas the intermediates between phytoene and 0-carotene appear sequentially during photoinduction in F. aquaeductuum (Bindl et al, 1970), IL CT-assa (Zalokar, 1954;Rau and Rau-Hund, 1977; and ÎL agariclDum (Valadon and Mummery, 1971). …”

“…N. crassa. Zalokar, 1954 ;Rau and Rau-Hund, 1977;. A. giganteus belongs to the latter category, as it forms ^-carotene only in the light (Gardner, 1949;Zurzycka, 1963 Trinci^Rq/?jrtfi^,MMj8 ince these early studies, however, no investigations have been reported concerning the mechanism of photoregulation in Aspergillus • '…”

“…In contrast to other fungi such as leurospora (Zalokar, 1954), no phytoene accumulates in dark- A typical time course for carotene production at 3 5 'C is shown in Figure 4:1B.…”

“…The latter two stages are light-independent but temperature-dependent. Goldstrohm and Lilly, (1965) Fusarium aquaeductuum Rau and Theimer, (1970) F. coerul1 urn Rau, (1975) F. oxysporlum Carlile, (1956) Neurospora crassa Zalokar (1954); Harding and Mitchell, (1968) N. sitophllla Ishi and Akayi, (1948) Pyronema conflueDs Carlile and Friend, (1956) Sphaerobolus stellatus Friederichsen and Engel, (1951) Syzygites megalocarpus Venger and Lilly, (1966) Verticillium agarlcinum Valadon and Mummery, (1971) The primary chemical reaction has generally been shown to be independent of temperature (Zalokar, 1954;Rilling, 1962;Mathews, 1963;Valadon ^ ^M»v\e^,1971 ;Seviour and Codar, 1973;Harding, 1974;. In several cases a "memory" of the light treatment has been found.…”

Effect of Light on Nonphotosynthetic Microorganisms

“…Besides bacteria, it has also been reported that a number of fungi,e.g.,Neurospora crassa [15,26,27], Fusarium aquaeductuum [8,[12][13][14] , Cephalosporeum diospyri [19] and others [6,7,22,23] can be photoinduced to synthesize carotenoids.…”