Studies of tryptic and peptic digestion of extracts of giant ragweed pollen

Harsh, George F.; Huber, Harry L.

doi:10.1016/s0021-8707(43)90361-2

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1944

1958

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Cited by 8 publications

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“…Pancreatin digestion was said to intensify the reactivity of these extracts, but details of the technique used were not given (9). Harsh and Huber found that peptic or tryptic digestion of giant ragweed pollen caused a marked loss of activity of the antigen, as measured by scratch and intracutaneous tests (4). A small but constant amount of activity which was unaffected by proteolytic digestion remained.…”

Section: Discussionmentioning

confidence: 99%

“…Attempts to demonstrate reactivity in these animals by skin tests and flocculation tests on the blood serum were unsuccessful. Because some investigators have found that digestion may alter the reactivity of pollens, it was thought that the negative results might have been due to digestion of the trichinella antigen (3,4). The present study was undertaken to determine whether or not peptic or tryptic digestion would deactivate the antigen of killed trichinae.…”

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confidence: 96%

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