Studies of the Carrier State Following Infection With Group a Streptococci. I. Effect of Climate*

A Three-Year Prospective Study of Streptococcal Infections in a Population of Rural Egyptian School Children

“…In general, from the evidence presented, this would not appear to be the case in Egypt, but a possible difference may be in the unusually mild nature of streptococcal pharyngitis here. In no instance, for example, was a child seen with exudative pharyngitis similar to that reported among U.S. servicemen at Warren Air Force Base, Wyoming (Krause et al, 1962). It should be stressed, however, that exudate is a less reliable indicator of streptococcal pharyngitis in children than it is in adults (Kaplan et al, 1971).…”

Studies of the Carrier State Following Infection With Group a Streptococci. Ii. Infectivity of Streptococci Isolated During Acute Pharyngitis and During the Carrier State*

“…He received no specific therapy and 2 weeks later was transferred by airplane to Florida (1). Cultures of the nose and oropharynx were obtained twice weekly by methods previously described (1).…”

“…He received no specific therapy and 2 weeks later was transferred by airplane to Florida (1). Cultures of the nose and oropharynx were obtained twice weekly by methods previously described (1). Colonies of bacteria showing p-hemolysis were isolated from the original sheep blood-agar plates and transferred to a second blood-agar plate.…”

“…Group A streptococci persist in the tissues of the upper respiratory tract for several months after infection (1), although the number of streptococci that can be isolated from the respiratory tract usually decreases after the acute illness. The present study was designed to test the infectivity of group A streptococci isolated from the human oropharynx during the acute streptococcal infection and during the carrier state.…”

T. Duckett Jones and rheumatic fever in 1986. T. Duckett Jones Memorial Lecture.

“…The data in this figure were all taken from studies done at the Streptococcus Laboratory in Wyoming. 16 17 I have taken the liberty of comparing data from different studies, which might not be scientifically very palatable, but which I believe is accurate enough to make my points. The duration of carriage after untreated infections was quite long; at the end of 11 weeks, we were still able to detect streptococci in about 90% of young airmen.…”