Studies of the 1000 Cases of Early Gastric Cancer

Ohta, Hiroyuki; Takagi, Kunio; Ohashi, Ichiro; Tamura, Shinji; Kuno, K; Kajitani, Tamaki; Kato, Yukio

doi:10.5833/jjgs.14.1399

Cited by 16 publications

(7 citation statements)

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“…Approximately 70% of our patients with early gastric cancer had lesions of the depressed type, which was in accord with previous observations [4,19,20]. The incidences of other gross types and m-or sin-cancer were also much the same as those reported earlier [6,12,13,20,21].…”

Section: Discussionsupporting

confidence: 92%

Surgical approach to early gastric cancer with lymph node metastasis

et al. 1989

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The clinicopathology of our series of patients (n = 486) with early gastric cancer was reviewed with special reference to metastasis to the regional lymph nodes. The incidence of lymph node metastasis was 15.8% (19/120) in patients with the protruded type of carcinoma and 11.7% (42/360) in patients with the depressed type of carcinoma. It was especially high in carcinomas of the IIa + IIc type of the former group. The incidence of lymph node involvement was higher in the group with larger tumors (greater than 30 mm) than in the group with smaller tumors (less than or equal to 30 mm). Metastatic lesions were detected in as many as 25.0% (16/64) of the cases with large tumors (greater than or equal to 50 mm); however, of the 46 cases with small tumors (less than 10 mm), 1 case had metastases to the nodes of group 1. There were 4 cases of m-cancer with metastasis to group 1 lymph nodes. Skip metastasis to group 2 lymph nodes was discovered in 4 cases. From these results, we feel that the standard operation for early gastric cancer is R2-gastrectomy including the complete removal of group 1 and 2 lymph nodes. R1-gastrectomy or local resection is thought to be sufficient for m-cancer with a lesion smaller than 10 mm in maximum diameter.

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Section: Discussionsupporting

confidence: 92%

Surgical approach to early gastric cancer with lymph node metastasis

et al. 1989

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“…The pathological findings in our series bave been compared with those in 1,000 cases of single early gastric carcinoma reported by Ohta and co-workers [2]. lesions with a different histological picture without mucosa intervening.…”

Section: Type IIImentioning

confidence: 61%

“…rates for gastric malignancy [2]. In addition, more cases of multiple carcinoma have been encountered.…”

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confidence: 99%

Synchronous multiple early gastric carcinoma: A study of 178 cases

et al. 1985

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Over the past 3 decades, ending in 1979, resection has been performed in 7,220 patients with gastric carcinoma. Synchronous multiple gastric carcinoma, according to the diagnostic criteria of Moertel, was found in 468, of which 178 (38%) were "early." There were 135 double, 33 triple, and 10 quadruple early earcinomas. Fewer than one-third of the smaller tumors were diagnosed preoperatively, and 61.5% of the smaller lesions were less than 10 mm in diameter. In 53% of the patients, the smaller lesions were in the lower one-third of the stomach with the main lesion in the upper one-third, whereas in 13% the smaller neoplasms were iocated in the upper one-third of the stomach with the main lesion in the Iower one-third. The clinical significance of the smaller lesions was their location relative to the resection line. When planning treatment of gastric carcinoma, it is important to evaluate the whole stomach before and during the operation and after examining the resected specimen. The 5-year survival rate for patients with multiple early gastric carcinoma was 85.8%.The concept of the management of early gastric carcinoma bas evolved since the first description by Verse in 1908 [1]. Recently, we have achieved an increase in the detection of early gastric carcinoma by improved diagnosis principally due to fiberoptic instruments. In 1980 Ohta et al. [2] reported that more than one-third of the resected gastric carcinomas (108 of 277 cases) at the Cancer Institute Hospital in Tokyo were "early." The frequency of early cancer has also increased in the United States [3] and in Europe [4]. This increase has contributed significantly to the recent improvement in survival

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“…Patients with stomach or colon carcinomas whose invasion is limited to the mucosa or submucosa generally have a good prognosis; the 5-year survival rates are 90 -95%. 2 With esophageal squamous cell carcinomas, however, the 5-year survival rate for submucosal cases has been reported to be worse (33-69%) than for intramucosal lesions (83-100%). [3][4][5][6][7] The molecular mechanisms have yet to be clarified.…”

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confidence: 99%