Studies of Streptococcal Prophylaxis Comparison of Oral Penicillin and Benzathine Penicillin

Chancey, R. L.; Morris, Alton J.; Conner, R. H.; Catanzaro, Frank; Chamovitz, Robert; Rammelkamp, Charles H.

doi:10.1097/00000441-195502000-00007

Cited by 32 publications

(4 citation statements)

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“…Shortly after the introduction of penicillin for the treatment of bacterial infections in man, allergic reactions were found to occur with a frequency of h2 to S-T]\, (National Research Council, 1943;Lepperc/a/., 1949). These reactions were more common after parenteral than oral administration and were most often manifest as urticaria or angio-oedema (Chancery, 1955). Similarly, skin rashes have been observed following treatment with ampicillin, the widest used semisynthetic penicillin, with a prevalence as high as 9% (Boston Collaborative Drug Surveillance Program.…”

Section: Introductionmentioning

confidence: 99%

Asthma due to inhaled chemical agents: ampicillin, benzyl penicillin, 6 amino penicillanic acid and related substances

Davfes

Hendrick

Pepys

1974

Clin Experimental Allergy

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Summary Three out of four workers from an antibiotic‐producing factory developed late asthma and eosinophilia on inhalation challenge testing with ampicillin and related substances. The chemicals to which each worker reacted varied, suggesting differences in the clinically important allergens for each individual. The taking by mouth of ampicillin in one patient, and benzyl penicillin in another in therapeutic doses led to the development of late asthma accompanied by skin and gastro‐intestinal disturbances. The inhalation of 200 μg of beclomethasone dipropionate before in one case, and before and 3‐hourly after provocation challenge in the other, blocked the late asthmatic reaction. 40 mg sodium cromoglycate similarly given failed to inhibit the reactions. In one patient, 04416–0.24 mg of isoprenaline sulphate inhaled 10 min before or 60 min after inhalation testing prevented the development of late asthma, and when given during the asthmatic reaction led to its rapid reversal.

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Section: Introductionmentioning

confidence: 99%

Asthma due to inhaled chemical agents: ampicillin, benzyl penicillin, 6 amino penicillanic acid and related substances

Davfes

Hendrick

Pepys

1974

Clin Experimental Allergy

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“…A high proportion of the most susceptible and heavily infected groups are thus treated and the carrier rate appears to be markedly suppressed for a number of weeks. As was true of the military experiences 14-41, 18,19 250,000 units of potassium penicillin G, twice daily by mouth for 10 days, was found to be effective.…”

Section: Discussionmentioning

confidence: 77%

“…Oral [12][13][14][15][16][17][18][19][20] and injected 12,19,[21][22][23] pen-icillin have been found to be effective in the control of streptococcal epidemics providing that at least 250,000 units are administered twice daily for 10 days by the oral route and penicillin is available in the host for a similar period when the parenteral route is utilized. …”

mentioning

confidence: 99%

Epidemiology of Civilian Streptococcal Outbreaks Before and After Penicillin Prophylaxis

Poskanzer¹,

Feldman²,

Beadenkopf³

et al. 1956

Am J Public Health Nations Health

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“…A case was defined as the occurrence of at least one outpatient diagnosis of a GAS-related illness (ICD-9-CM codes: 034.0, 035, 038.0, 041.01, 320.2, 390-392, 482.31), a minimum of 30 days (the estimated protective effect from a single dose of BPG) after the start of BCT [10]. The latter criterion was employed to avoid bias that may be introduced into the study results due to the selective administration of BPG at Fts.…”

Section: Methodsmentioning

confidence: 99%

Influenza immunization and subsequent diagnoses of group A streptococcus-illnesses among U.S. Army trainees, 2002–2006

Lee

Eick

Bloom

et al. 2008

Vaccine

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To assess the association between influenza immunization and subsequent diagnosis of group A streptococcus (GAS)-illness in Army recruits during influenza seasons 2002-2006. A case-control study was employed with cases as trainees with outpatient GAS diagnosis (ICD-9-CM codes: 034.0, 035, 038.0, 041.01, 320.2, 390-392, 482.31) during the influenza season, and controls as trainees with no outpatient GAS diagnosis during the influenza season. Primary exposure was influenza immunization during 1st September to 30th April of each season. Estimated protective effects of influenza immunization against GAS-illness ranged from 50% to 77%. A strong protective effect was suggested for Army trainee influenza immunization on the diagnosis of GAS-illness.

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Studies of Streptococcal Prophylaxis Comparison of Oral Penicillin and Benzathine Penicillin

Cited by 32 publications

References 0 publications

Asthma due to inhaled chemical agents: ampicillin, benzyl penicillin, 6 amino penicillanic acid and related substances

Asthma due to inhaled chemical agents: ampicillin, benzyl penicillin, 6 amino penicillanic acid and related substances

Epidemiology of Civilian Streptococcal Outbreaks Before and After Penicillin Prophylaxis

Influenza immunization and subsequent diagnoses of group A streptococcus-illnesses among U.S. Army trainees, 2002–2006

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