Studies of CoQ10 and cyclodextrin complexes: solubility, thermo- and photo-stability

Structural and Solubility Characteristics of Coenzyme Q10Complexes Including Cyclodextrin and Starch

“…Cyclodextrin과 coenzyme Q 10 은 복합체를 형성한다고 이미 연 구되었다 (28)(29)(30)(31)(32)(33)(34). 본 연구는 선행연구를 통해 γ-cyclodextrin으로 cyclodextrin을 선정한 뒤 coenzyme Q 10 과 복합체 형성을 유도하 였으며 그 결과를 사진으로 나타내었다 (Fig.…”

“…또한 coenzyme Q 10 의 경우 구조상 큰 잔기를 포함하고 있기 때문에 포접할 수 있는 내부공동이 가장 큰 γ-cyclodextrin 이 복합체를 형성할 수 있는 확률이 가장 크기 때문에 coenzyme Q 10 과 복합체를 형성함에 있어 가장 유리할 것이라고 보고하였다 (28)(29)(30)(31). 뿐만 아니라 coenzyme Q 10 -cyclodextrin 복합체를 제조후 복합체의 용해도, 열 및 광 안정성 개선, 생체이용율 개선을 보 고한바 있다 (32)(33)(34)(35).…”

Microencapsulation of ubiquinone-10 in carbohydrate matrices for improved stability

“…Stability of free and microencapsulated CoQ10 was studied under UV light over a period of 2 h as reported by Fir, Smidovnik, Milivojevic, Zmitek, and Prosek (2009). The wavelength of UV light was 254 nm and distance between sample and UV lamp was 15 cm.…”

Microencapsulation of ubiquinone using complex coacervation for functional yoghurt

“…Different approaches to increasing the solubility of CoQ10 have been attempted, such as complexation with cyclodextrins (4,5), use of polysorbate 80 and medium chain triglycerides (6), micellar solution with polyoxyethylene (60) (7), self-emulsifying drug delivery systems using a mixture of surfactant, oil, and co-surfactant (8), solid dispersion using poloxamer 407 (9), microencapsulation using different blends of Gum Arabic, maltodextrin, and modified starches as wall materials (10), and aqueous dispersion of CoQ10 nanoparticles using amylomaize starch or dextrin (11).…”