2020
DOI: 10.1002/dta.2763
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Studies of athlete biological passport biomarkers and clinical parameters in male and female users of anabolic androgenic steroids and other doping agents

Abstract: The use of anabolic androgenic steroids (AAS) and other performance enhancing substances can change over time, so there is a need to constantly update what substances are used and can be detected. Six women and 30 men anabolic androgenic steroid users were recruited who filled out an anonymous questionnaire about their use of performance enhancing substances during the past year. Sampling took place on a single occasion and included blood and urine collection. Our aim was to identify which doping agents can be… Show more

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Cited by 31 publications
(53 citation statements)
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References 42 publications
(88 reference statements)
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“…The relevance and routine applicability of testing serum T in routine doping controls was highlighted by Handelsman and Bermon, who reported on two cases of serial serum T measurements in female athletes, where the pattern of T concentrations was not found to be consistent with any normal physiological profile. 80 The corresponding urinary steroid profile remained unremarkable, a phenomenon also reported by Börjesson, 46…”
Section: Steroid Profiling In Urine and Serumsupporting
confidence: 58%
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“…The relevance and routine applicability of testing serum T in routine doping controls was highlighted by Handelsman and Bermon, who reported on two cases of serial serum T measurements in female athletes, where the pattern of T concentrations was not found to be consistent with any normal physiological profile. 80 The corresponding urinary steroid profile remained unremarkable, a phenomenon also reported by Börjesson, 46…”
Section: Steroid Profiling In Urine and Serumsupporting
confidence: 58%
“…The relevance and routine applicability of testing serum T in routine doping controls was highlighted by Handelsman and Bermon, who reported on two cases of serial serum T measurements in female athletes, where the pattern of T concentrations was not found to be consistent with any normal physiological profile 80 . The corresponding urinary steroid profile remained unremarkable, a phenomenon also reported by Börjesson, 46 thus underlining the importance of complementing urinary steroidal module of the ABP with serum steroid profile data or, at least, with blood T values determined, for example, from dried blood spots (DBS) 81 …”
Section: Anabolic Agentsmentioning
confidence: 82%
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“…Finally, this study was conducted around 20 years ago. However, as the AAS use pattern appears to be similar in Sweden today [49] (daily communication with AAS users via the Anti-Doping Hot-Line), we believe that the results are still representative, although there is a tendency towards continuous AAS use [49] rather than AAS use in cycles.…”
Section: Discussionmentioning
confidence: 68%
“…In addition to the large intra‐individual variation seen in E concentrations in women, another gender dilemma is that after T administration, urinary E excretion is not down‐regulated in women in contrary to men, regardless of UGT2B17 genotype 33,34 . Consequently, T administration in women is not necessarily associated with elevated T/E 35,36 . In addition to monitoring the urinary T/E ratio, future testing programs should consider monitoring serum T and/or other serum markers, 37 which may improve the chance to identify women doping with T 35 …”
Section: Discussionmentioning
confidence: 99%