“…The classification of non-Hodgkin lymphoma has been revised several times since its first description by Wieland in 1901. 23 Before Rappaport's 12 effort to classify these lymphomas according to cytomorphology and growth pattern, terms like lymphosarcoma, reticulum cell sarcoma, and follicular lymphoma were used. In 1974, Lukes and Collins 6 proposed a classification system that is based on immunologic markers of the tumor cells.…”