Struktur und Eigenschaften der Isophoronglyoxylsäureester

Abstract

Fur die aus Isophoron und Oxalestern entstehenden Isophoronglyoxylsaureester wird Struktur 2 bewiesen. Structure and Properties of IsophoronylglyoxylatesIsophoronylglyoxylates from isophoron and oxalic esters have structure 2.

Molecular design and physical properties of highly functionalized configurationally locked polyenes – an experimental and theoretical study

“…The synthesis of compounds with R 1 ¼ I-VII is according to the classical synthetic schemes reported by Schiff and Lemke. [48][49][50][51][52][53][54][55][56][57] The important specics are discussed for each of the subclasses. Equimolar amounts of isophorone (3,5,5-trimethyl-2-cyclohexene-1-one) (Sigma-Aldrich, purum >97.0%) and corresponding aromatic aldehydes are mixed in 50 mL toluene (or methanol) with stirring at r.t. for 6 h. To the reaction mixtures are added ˛2-10 mL concentrated CH 3 COOH and 3 drops piperidine or 5 mL of a 0.1 M solution of L-proline dissolved in water, which acts as a catalyst.…”

“…The R 1 -substituents for the highly functionalized derivatives 6, 10, 11, 14, 15, 17, 18 and 21 are obtained according to the pathways reported. 55…”

“…They are unfortunately characterized by complex synthetic behaviour, low yields and several competitive unwanted reactions, under the classical Lemke or Schiff schemes. [48][49][50][51][52][53][54][55][56][57] These derivatives however allowed isolation of 1D-3D crystals, in parallel thin lms and polymers, due to the polymerization of the nucleoside residues. Therefore further efforts towards the improvement of the synthetic reactions are justied for 47-50 and 71-73, respectively.…”

“…Thus: (i) the obtained derivatives primarily could be isolated as 1D-3D crystals and/or thin lms (Scheme 1); (ii) analogues with morpholine fragments at the R 2position oen underwent cleavage of the ring; and (iii) optimization of reaction conditions is necessary for compounds with S-containing analogues at the R 1 position, due to the redox processes that occur; (iv) the CLPs are obtained at 5-7 staging synthesis in ionic liquids. [48][49][50][51][52][53][54][55][56][57] It is of particular importance to note that the MS techniques involving the MALDI-MS method Journal of Materials Chemistry C Paper allowed direct crystalline phase analysis, in addition to the NLO and THz-characterization of thin and ultra-thin lm phases. On the other hand, the possibility for obtaining the protonated forms of the CLPs by the interaction with the polyfunctional acids as more preferred materials, particularly those used as matrices in the MALDI-MS imaging assay, provides a new direction for further studies.…”