Structures of three forms of the purine base precursor 5(4)-amino-1H-imidazole-4(5)-carboxamide (AICA): AICA.C₃H₇OH, AICA.H₂O and HAICA⁺.H₂PO₄ ⁻

Abstract

C4H6N40.C3HTOH is monoclinic, space group P21/c, . Similarly the geometry of AICA in AICA. C3H7OH resembles the AICA part in the corresponding nucleoside (AICAR). In each molecule the 4-carboxamide moiety is oriented so that a strong intramolecular hydrogen bond is formed to the 5-amino group of the heterocycle.