Structures of Naphthoquinones Produced by the Fungus,Fusariumsp., and Their Biological Activity toward Pollen Germination

Anthraquinone, Cyclopentanone, and Naphthoquinone Derivatives from the Sea Fan-Derived Fungi Fusarium spp. PSU-F14 and PSU-F135

“…Its molecular formula, C 29 H 26 O 11 , by HREIMS indicated that 4 had 17 degrees of unsaturation. The presence of UV absorption bands at 227, 275, 296, 403, 473, 500, 535, and 571 nm indicated the existence of a 1,4-naphthoquinone chromophore . Furthermore, a hydroxy absorption band was found at 3470 cm −1 , while carbonyl ones were found at 1717 and 1644 cm −1 , in the IR spectrum.…”

“…Compound 9 was isolated as its 11-acetoxy derivative. Moreover, nine known compounds, aspergillol B, (+)-solaninol ( 12 ), javanicin ( 13 ), 5-hydroxy-8-methoxy-2,4-dimethylnaphtho[1,2- b ]furan-6,9-dione ( 14 ), 2,3-dihydro-5-hydroxy-8-methoxy-2,4-dimethylnaphtho[1,2- b ]furan-6,9-dione ( 15 ), fusarubin ( 16 ), methyl ether fusarubin ( 17 ), anhydrofusarubin ( 18 ), and tyrosol, were obtained from the broth extract of Fusarium sp. PSU-F135.…”

Cytotoxic naphthoquinone and a new succinate ester from the soil fungus Fusarium solani PSU-RSPG227

“…Two new metabolites, 25 solaninaphthoquinone (1) and 4-(4-hydroxyphenethoxy)-4-oxo-26 butanoic acid (2), together with five previously reported com-27 pounds: javanicin (3) (Kimura et al, 1988), monaspilosin (4) 28 (Cheng et al, 2008), aspergillol B (5) (Pettit et al, 2009;Wang et al, 29 2009), tyrosol (6) (Rukachaisirikul et al, 2010) and 4-hydro-30 xyphenylacetic acid (7) (Bala Show Reddy and Dhananjaya, 2000) 31 were isolated from the ethyl acetate extract of the culture broth of 32 F. solani PSU-RSPG227 (Fig. 1).…”

Bioactive Dihydronaphthoquinone Derivatives from Fusarium solani

“…13 In this study, we report on the isolation, structural elucidation, and biological activities of new dihydronaphthoquinone derivatives, karuquinone A (1), karuquinone B (2), and karuquinone C (3). Three known naphthoquinones, javanicin (4), 14 2,3-dihydro-5-hydroxy-8methoxy-2,4-dimethylnaphtho[1,2-b]furan-6,9-dione (5), 15 and 5-hydroxydihydrofusarubin C (6), 16 are also described. Isolated metabolites were evaluated for their cytotoxicity against four different cell lines.…”