Structures involved in production, secretion and injection of the venom produced by the caterpillar Lonomia obliqua (Lepidoptera, Saturniidae)

Veiga, Ana Beatriz Gorini da; Blochtein, Betina; Guimarães, Jorge A.

doi:10.1016/s0041-0101(01)00086-1

Cited by 66 publications

(47 citation statements)

References 6 publications

(20 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[485] Caterpillars can pressurize the lumen of the secretory apparatus to inject considerable volumes of poison; [486] the tips of spines and hairs also often detach easily into the skin of the attacker. [488,489] True setae have a fundamentally different mechanism of action. These are typically much smaller than other urticating structures at 100-500 µm long and only 2-10 µm in dia meter.…”

Section: Anatomical Structures For Allomone Injectionmentioning

confidence: 99%

It's Not a Bug, It's a Feature: Functional Materials in Insects

2018

View full text Add to dashboard Cite

Over the course of their wildly successful proliferation across the earth, the insects as a taxon have evolved enviable adaptations to their diverse habitats, which include adhesives, locomotor systems, hydrophobic surfaces, and sensors and actuators that transduce mechanical, acoustic, optical, thermal, and chemical signals. Insect‐inspired designs currently appear in a range of contexts, including antireflective coatings, optical displays, and computing algorithms. However, as over one million distinct and highly specialized species of insects have colonized nearly all habitable regions on the planet, they still provide a largely untapped pool of unique problem‐solving strategies. With the intent of providing materials scientists and engineers with a muse for the next generation of bioinspired materials, here, a selection of some of the most spectacular adaptations that insects have evolved is assembled and organized by function. The insects presented display dazzling optical properties as a result of natural photonic crystals, precise hierarchical patterns that span length scales from nanometers to millimeters, and formidable defense mechanisms that deploy an arsenal of chemical weaponry. Successful mimicry of these adaptations may facilitate technological solutions to as wide a range of problems as they solve in the insects that originated them.

show abstract

Section: Anatomical Structures For Allomone Injectionmentioning

confidence: 99%

It's Not a Bug, It's a Feature: Functional Materials in Insects

2018

View full text Add to dashboard Cite

show abstract

“…These structures are hard and spiny evaginations of the cuticle, underneath which the toxins are stored. Often, the whole animal is smashed in the accident, the insect's chitinous bristles get broken and the venomous secretions, including hemolymph, penetrate the human skin and enter the circulation (Veiga et al, 2001a).…”

Section: Caterpillar Envenomationmentioning

confidence: 99%

Acute Kidney Injury Induced by Snake and Arthropod Venoms

Berger¹,

Vieira²,

Guimarães³

2012

Renal Failure - The Facts

View full text Add to dashboard Cite

“…Often, the whole animal is smashed in the accident. In the latter case, the insect's cuticle is broken and many secretions, including hemolymph, penetrate the human skin and enter the circulation (Veiga et al, 2001). While some toxic principles are found in bristle extract, others are present in the hemolymph of L. obliqua (Donato et al, 1998;Veiga et al, 2003).…”

Section: Introductionmentioning

confidence: 99%

A catalog for the transcripts from the venomous structures of the caterpillar Lonomia obliqua: Identification of the proteins potentially involved in the coagulation disorder and hemorrhagic syndrome

Veiga

Ribeiro

Guimarães

et al. 2005

Gene

View full text Add to dashboard Cite

Accidents with the caterpillar Lonomia obliqua are often associated with a coagulation disorder and hemorrhagic syndrome in humans. In the present study, we have constructed cDNA libraries from two venomous structures of the caterpillar, namely the tegument and the bristle. Highthroughput sequencing and bioinformatics analyses were performed in parallel. Over one thousand cDNAs were obtained and clustered to produce a database of 538 contigs and singletons (clusters) for the tegument library and 368 for the bristle library. We have thus identified dozens of fulllength cDNAs coding for proteins with sequence homology to snake venom prothrombin activator, trypsin-like enzymes, blood coagulation factors and prophenoloxidase cascade activators. We also report cDNA coding for cysteine proteases, Group III phospholipase A2, Ctype lectins, lipocalins, in addition to protease inhibitors including serpins, Kazal-type inhibitors, cystatins and trypsin inhibitor-like molecules. Antibacterial proteins and housekeeping genes are also described. A significant number of sequences were devoid of database matches, suggesting that their biologic function remains to be defined. We also report the N-terminus of the most abundant proteins present in the bristle, tegument, hemolymph, and "cryosecretion". Thus, we have created a catalog that contains the predicted molecular weight, isoelectric point, accession number, and putative function for each selected molecule from the venomous structures of L. obliqua. The role of these molecules in the coagulation disorder and hemorrhagic syndrome caused by envenomation with this caterpillar is discussed. All sequence information and the Supplemental Data, including Figures and Tables with hyperlinks to FASTA-formatted files for each contig and the best match to the Databases, are available at http://www.ncbi.nih.gov/projects/omes.

show abstract

Structures involved in production, secretion and injection of the venom produced by the caterpillar Lonomia obliqua (Lepidoptera, Saturniidae)

Cited by 66 publications

References 6 publications

It's Not a Bug, It's a Feature: Functional Materials in Insects

It's Not a Bug, It's a Feature: Functional Materials in Insects

Acute Kidney Injury Induced by Snake and Arthropod Venoms

A catalog for the transcripts from the venomous structures of the caterpillar Lonomia obliqua: Identification of the proteins potentially involved in the coagulation disorder and hemorrhagic syndrome

Contact Info

Product

Resources

About