Structure of the lipopolysaccharide O-antigen of Aeromonas encheleia strain A4 representing the new PGO1 serogroup of aeromonads prevailing in Polish aquaculture

Chemical investigation of the hydnoid fungus Sarcodontia setosa resulted in the isolation of five compounds, including two new sarcodontic acid derivativessetosic acid (1) and 7,8dehydrohomosarcodontic acid (2) along with three known benzoquinone pigmentssarcodontic acid (3), 4,5-dehydrosarcodontic acid (4) and dihydrosarcodontic acid (5). The structures were elucidated using spectroscopic methods (UV, NMR, HR-ESIMS). The biosynthetic relationship of the isolated compounds is proposed and discussed. Antibacterial activity screening of 2 compounds 1-5 against ESKAPE bacterial strains in vitro with zones of inhibition was performed and MIC values were established for the most active compounds (3 and 5).

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Structure of the lipopolysaccharide O-antigen of Aeromonas encheleia strain A4 representing the new PGO1 serogroup of aeromonads prevailing in Polish aquaculture

Cited by 3 publications

References 38 publications

Structure and gene cluster annotation of the O-antigen of Aeromonas sobria strain K928 isolated from common carp and classified into the new Aeromonas PGO1 serogroup

Structure and gene cluster annotation of the O-antigen of Aeromonas sobria strain K928 isolated from common carp and classified into the new Aeromonas PGO1 serogroup

Immunochemical studies and gene cluster relationships of closely related O-antigens of Aeromonas hydrophila Pt679, Aeromonas popoffii A4, and Aeromonas sobria K928 strains classified into the PGO1 serogroup dominant in Polish aquaculture of carp and rainbow trout

New benzoquinone pigments from the hydnoid fungus Sarcodontia setosa and their biosynthetic relationship

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