Structure and Mechanical Properties of Retrograded Rice Starch and Cow Bone Powder Composite Sponge

Abstract

To study the effect of addition purified cow bone (CB) powder (20, 30, 40 and 50 wt%) in slurry suspension of retrograded rice starch (RRS). The composite sponges were used as in bone repair. The RRS-CB composite sponges were prepared from the mixture of RRS, CB and additive into distill water. The prepared samples were characterized including SEM, XRD, physical and mechanical properties. The results of optimized condition have shown the samples of 40 wt% CB that had the swelling rate as 102± 0.01%, area of expansion was 20 ± 0.03 % for 72 hours and the compressive strength was 64.35±0.05KPa. In addition, it was found that this content resulted in sufficient soft porous material, foldable by hand and self recovered body.

<i>In Vivo</i> Clinical Trial of Porous Starch-Hydroxyapatite Composite Biomaterials for Bone Regeneration

“…In earlier invention, we have produced porous starch-HA composite. Starch is Thai rice medical grade powder which approved by Health Ministry of Thailand and we have confirmed biocompatibility test in another laboratory animal experimentation [10,11] and also it has passed animal biocompatibility test. So to decrease the number animal life used for research purposes, we avoided our products, porous starch-HA composite, from in vivo animal testing.…”