Structural Strategies for Supramolecular Hydrogels and Their Applications

Abstract

Supramolecular structures are of great interest due to their applicability in various scientific and industrial fields. The sensible definition of supramolecular molecules is being set by investigators who, because of the different sensitivities of their methods and observational timescales, may have different views on as to what constitutes these supramolecular structures. Furthermore, diverse polymers have been found to offer unique avenues for multifunctional systems with properties in industrial medicine applications. Aspects of this review provide different conceptual strategies to address the molecular design, properties, and potential applications of self-assembly materials and the use of metal coordination as a feasible and useful strategy for constructing complex supramolecular structures. This review also addresses systems that are based on hydrogel chemistry and the enormous opportunities to design specific structures for applications that demand enormous specificity. According to the current research status on supramolecular hydrogels, the central ideas in the present review are classic topics that, however, are and will be of great importance, especially the hydrogels that have substantial potential applications in drug delivery systems, ophthalmic products, adhesive hydrogels, and electrically conductive hydrogels. The potential interest shown in the technology involving supramolecular hydrogels is clear from what we can retrieve from the Web of Science.

Harnessing the Potential of Self‐Assembled Peptide Hydrogels for Neural Regeneration and Tissue Engineering

“…[200] SAPs have long been considered effective supramolecular hydrogel materials that typically do not require reagents like initiators, catalysts, or enzymes, and are safe with minimal inflammation and scar formation for tissue regeneration. [201] The SAPs' bottom-up design makes them highly customizable injectable hydrogels. Their tunable molecular design and intramolecular interactions enable us to ensure that their bioactive, topographical, mechanical, and electrical characteristics align with the criteria for neural tissue regeneration.…”

The Potentials and Challenges of Hydrogels for Ocular Therapy

“…Fernandes-Cunha et al [63] designed a supramolecular hydrogel composed of adamantane in combination with hyaluronic acid or cyclodextrin for corneal wound healing. Other forms of supramolecular hydrogel systems like adhesive hydrogels, self-healing hydrogels, electrically-conducting hydrogels, and metallo-supramolecular hydrogels have been highlighted elsewhere [64].…”

Synthesis, Spectroscopic Analysis, and Anti-Bacterial Studies of Pd(II) Complexes of Phosphine and Hydrazone Derivatives

“…), and materials science. For instance, catalytic applications could include oxidation, reduction, and cross-coupling reactions (11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21).…”