Structural, physical characteristics and biological activities assessment of scleroglucan from a local strain Athelia rolfsii TEMG

Fungal exopolysaccharides: Properties, sources, modifications, and biomedical applications

“…The extraction approach of fungal EPSs is a function of the source, structure, and required degree of purity (Elsehemy et al, 2020;Zhu, Du, & Xu, 2016). For example, lentinan (from common edible mushroom Lentinus edodes) is extracted by ethanol precipitation, solubilized by acetic acid followed by chromatographic column purification (Venkatachalam, Arumugam, & Doble, 2020).…”

“…The fungal EPSs are diverse in the monosaccharide linkage patterns, monosaccharide units, molecular mass, branching degree, glycosidic bond, and conformation (Asadi et al, 2021;Gong et al, 2020). In addition, EPSs comprised of similar monosaccharide entities produced by various fungi had distinct molecular weights (MWs) (Elsehemy et al, 2020). Fungal EPSs may present several structures such as extracellular glucan characterized by β-(1,3)-D-pyran glycosidic bonding, αmonosaccharides configuration with predominantly 1, 6 linkages, or α-(1,6) maltotriose sub-units produced from Lachnum sp.…”

“…In comparison to marine or plant-based PSs, microbial EPSs production only require a few days, do not compete with production lands, agro-industrial waste can be used as their feed, and are frequently simple to extract and purify Elsehemy et al, 2020) with typical production yields ranging from 0.0022-100 g/L Freitas, Torres, & Reis, 2017). Some fungi such as Aureobasidium pullulans can produce more than 40 g/L EPS (pullulan) under elementary production states (Luft et al, 2020).…”

“…Microbial EPSs yield varies based on the type of the strain and factors such as the conditions of the fermentation parameters such as pH, temperature, etc. (Elsehemy et al, 2020;Okoro, Gholipour, Sedighi, Shavandi, & Hamidi, 2021;Saadat, Khosroushahi, & Gargari, 2021;Shanmugam & Abirami, 2019).…”

Efficient Production of Scleroglucan by Sclerotium rolfsii and Insights Into Molecular Weight Modification by High-Pressure Homogenization

“…This characteristic of high branching frequency endows scleroglucan with high water solubility different to other types of β-glucans. In addition, scleroglucan is reported to have a higher molecular weight (Tan et al, 2019;Elsehemy et al, 2020). Due to these outstanding properties of a unique chemical structure and higher molecular weight, scleroglucan has significant advantages in terms of water solubility, biocompatibility, pseudoplasticity, resistance to hydrolysis, salt tolerance, moisture retention and viscosity stability (Barcelos et al, 2020;Song et al, 2020).…”