Structural, magnetic, electrochemical, catalytic, DNA binding and cleavage studies of new macrocyclic binuclear copper(II) complexes

Spectral, Magnetic, Electrochemical, Photochemical, DNA Binding and Cleavage, Catalytic and Biological Studies of 2, 2'-Bipyridyl Based d-f Hetero Binuclear Gd(III) and Cu(II) Complexes

“…The slope was determined by the method of initial rates by monitoring the growth of the 390 nm band of the product o-quinone. A linear relationship for initial rate and the complex concentration obtained for [GdCuL [1][2][3][4][5] (bpy) 2 ] complexes show a first-order dependence on the complex concentration for the systems.…”

“…The DNA was treated with the [GdCuL [1][2][3][4][5] (bpy) 2 ] complexes in different concentrations (20,40,60, 80 and 100 µM) fortified with 5 mM H 2 O 2 , 100 mM Tris-Hcl (pH 8.0) and 0.2 µg/µL of pBR 322 DNA. All the samples were incubated for 2 h at RT in both light and dark conditions.…”

“…Emission spectra of complexes [GdCuL [1][2][3][4][5] ] in DMF solution with excitation at 460 nm were shown in Figure 4. The fluorescence characteristics complexes were determined.…”

“…The catecholase activity of the [GdCuL [1][2][3][4][5] (bpy) 2 ] complexes synthesized in the present work was carried out using pyrocatechol as the convenient model substrate for the identification of functional models for the metalloenzymes 24 . For this purpose, 10 -3 mol dm -3 solutions of the complexes in dimethylformamide were treated with 100 equivalents of pyrocatechol in the presence of air.…”

“…[1][2][3] . Transition metal complexes with tunable coordination environments and versatile spectral and electrochemical properties offer a great scope of design for species that are suitable for catecholase, DNA binding and cleavage activities 4 . Hence, the synthesis of symmetrical and unsymmetrical binuclear Gd(III)Cu(II) complexes has gained more attention in recent years.…”