Structural features and hypoglycaemic effects of Cynomorium songaricum polysaccharides on STZ-induced rats

Wang, Junlong; Zhang, Ji; Zhao, Baotang; Wu, Yimin; Wang, Chunxia; Ruan, Roger

doi:10.1016/j.foodchem.2009.10.034

Cited by 40 publications

(20 citation statements)

References 28 publications

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“…In addition, CSPA can effectively improve serum insulin levels and glycogen content in diabetic rats. The histopathological study showed that CSPA can promote islet cell recovery to near normal levels [43]. These findings reveal the regulation of glucose metabolism by using C. songaricum.…”

Section: Regulation Of Glucose Metabolismmentioning

confidence: 61%

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Chemical constituents, and pharmacological and toxicological effects of Cynomorium songaricum: An overview

Cheng¹,

Zheng²,

Ma³

et al. 2018

Trop. J. Pharm Res

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Purpose: To review the chemical constituents, and the pharmacological and toxicological effects of Cynomorium songaricum (C. songaricum) and explore its potentials for further development as an alternative medicine.Methods: A large number of research articles related to "Cynomorium songaricum " "pharmacological effects", "toxicological effects" and "chemical composition" in English and Chinese language were retrieved through an extensive literature review using various electronic databases including Medline (1966Medline ( -2017 and EMBASE (1980EMBASE ( -2017

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Section: Regulation Of Glucose Metabolismmentioning

confidence: 61%

“…Aqueous extract of C. songaricum has promising effect against hydrocortisone-induced adrenal atrophy [43]. Yanga [44] reported the administration of C. songaricum extract to Wistar male rats for consecutively 56 days, resulting in the significant improvement in their sexual function.…”

Section: Effect Of the Plant Extract On The Reproductive Systemmentioning

confidence: 99%

Chemical constituents, and pharmacological and toxicological effects of Cynomorium songaricum: An overview

Cheng¹,

Zheng²,

Ma³

et al. 2018

Trop. J. Pharm Res

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“…Moreover, parts of the plant are edible, and hence not particularly toxic to humans. Yet at the same time, various products derived from it are biologically active, and have been used for centuries to treat common disorders, as they show certain antiemetic, aphrodisiac and hypotensive activities [8][9][10]. Furthermore, we have recently reported some aspects of the active compounds found in this plant and possible mode(s) of action associated with them [7].…”

Section: Introductionmentioning

confidence: 92%

Nanosizing Cynomorium: Thumbs up for Potential Antifungal Applications

et al. 2017

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Cynomorium coccineum L., the desert thumb, is a rather exotic, parasitic plant unable to engage in photosynthesis, yet rich in a variety of unique compounds with a wide spectrum of biological applications. Whilst extraction, separation and isolation of such compounds is time consuming, the particular properties of the plant, such as dryness, hardness and lack of chlorophyll, render it a prime target for possible nanosizing. The entire plant, the external layer (coat) as well as its peel, are readily milled and high pressure homogenized to yield small, mostly uniform spherical particles with diameters in the range of 300 to 600 nm. The best quality of particles is obtained for the processed entire plant. Based on initial screens for biological activity, it seems that these particles are particularly active against the pathogenic fungus Candida albicans, whilst no activity could be observed against the model nematode Steinernema feltiae. This activity is particularly pronounced in the case of the external layer, whilst the peeled part does not seem to inhibit growth of C. albicans. Thanks to the ease of sample preparation, the good quality of the nanosuspension obtained, and the interesting activity of this natural product, nanosized coats of Cynomorium may well provide a lead for future development and applications as "green" materials in the field of medicine, but also environmentally, for instance in agriculture.

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“…Previous reports ascribe several biological activities to Maltese Mushroom [Rosa et al, 2012;Wang et al, 2010;Zucca et al, 2013a], suggesting that its extract has a potential for use in nutraceutical formulations. Based on the possibility that Maltese Mushroom might be used for human nutrition, the nutritional facts for the whole plant were collected.…”

Section: Nutritional Facts Of Maltese Mushroommentioning

confidence: 99%

“…The pharmaceutical and ethnobotanical properties of Maltese Mushroom are also known and were recorded centuries ago. As even reported in the Bible [Duke, 2008], it has been utilized in antihemorrhoidal, aphrodisiac, hypotensive, antiemetic, and antitumor applications and in the stimulation of spermatogenesis [Dharmananda, 2011;Wang et al, 2010;Yang et al, 2010;Yu et al, 2010]. During famines, it was eaten by humans, and it is currently used in herbal infusions and other food preparations [Cui et al, 2013;Jin et al, 2014].…”

Section: Introductionmentioning

confidence: 99%

Biological Activities and Nutraceutical Potentials of Water Extracts from Different Parts of Cynomorium coccineum L. (Maltese Mushroom)

Zucca¹,

Argiolas²,

Nieddu³

et al. 2016

Pol. J. Food Nutr. Sci.

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Maltese Mushroom (Cynomorium coccineum L.) is a non-photosynthetic plant that has been used in traditional medicine for many centuries. In this paper, water extracts from the whole plant, external layer and peeled plant were studied to determine the main components responsible for its biological activities, i.e., its antimicrobial, antioxidant, and anti-tyrosinase activities; its cytotoxicity against mouse melanoma B16F10 cells; and its pro-erectile activity in adult male rats. The results of electron transfer and hydrogen transfer assays showed that the antioxidant activity was mainly due to anthocyanins in the external layer, whereas the external layer and peeled plant extracts both inhibited the microbial growth of several Gram-positive strains. In contrast, the whole plant extract had the highest anti-tyrosinase activity and exhibited pro-erectile activity when administered subcutaneously. Overall, this study elucidated which parts of Maltese Mushroom are responsible for its antimicrobial, antioxidant, and anti-tyrosinase activities and thus which extracts have potential for use in nutraceutical formulations.

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Structural features and hypoglycaemic effects of Cynomorium songaricum polysaccharides on STZ-induced rats

Cited by 40 publications

References 28 publications

Chemical constituents, and pharmacological and toxicological effects of Cynomorium songaricum: An overview

Chemical constituents, and pharmacological and toxicological effects of Cynomorium songaricum: An overview

Nanosizing Cynomorium: Thumbs up for Potential Antifungal Applications

Biological Activities and Nutraceutical Potentials of Water Extracts from Different Parts of Cynomorium coccineum L. (Maltese Mushroom)

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