Structural elucidation and synthesis of new components isolated from(piperaceae)

Chemical Constituents of the Roots of Piper Sarmentosum

“…Together with the MS data and comparison with the literature data, they were identified as N- [9-(3,4- 10) and N- [7-(3,4-methylenedioxyphenyl)-2E,6E-heptadienoyl]pyrrolidine (sarmentosine), 2) respectively. The amides 10 and 14 were identified from their spectral data to be N-pyrrolidyl-2E,4E-decadienamide (sarmentine) and N-isobutyl-2E,4E-decadienamide (pellitorine).…”

“…In Malaysia and the Indonesian Archipelago, the leaves and roots of this plant are used for the treatment of toothache, fungoid dermatitis on the feet, coughing, asthma and pleurisy. 1) In previous investigations of P. sarmentosum, several alkamides 2,3) and phenylpropanoids 4) were isolated from the fruits and leaves. We now report the isolation and structural elucidation of sixteen components from the fresh roots of P. sarmentosum.…”

New Insecticidal Amides from Petroleum Ether Extract of Dried Piper nigrum L. Whole Fruits

“…[1][2][3][4][5] In search of plant-based potent insecticides, [6][7][8][9][10] current investigations on the petroleum ether extract of the dried whole fruits of P. nigrum have resulted in the isolation of two new, seven hitherto unreported from this plant and eleven known compounds. Compounds isolated from petroleum ether extract included stigmastanol (3), 11) bsitosterol (4) 12) stigmasterol (5), 12) stigmastanol 3-O-b-D-glucopyranoside (6), 11,13) b-sitosterol 3-O-b-D-glucopyranoside (7), [13][14][15][16] [(2E,4E)-octadienoyl]-N-isobutylamide (8), 17) sarmentine (9), 18) [(2E,4E)-dodecadienoyl]-N-isobutylamide (10), 19) [(2E,4E)-dodecadienoyl]pyrrolidine (11) [4], hexadecanoic ethyl ester (12), 20) octadecanoic acid (13), 21) pellitorine (14) [18], hexadecanoylpyrrolidine (15), 22) [(2E)-octadecanoyl]pyrrolidine (16), 22) 1-[(2E,4E,12Z)-octadecatrienoyl]-N-isobutylamide (17), 23) piptaline (18), 24) 1-[7-(3,4-methylenedioxyphenyl)-(2E,4E)-heptadienoyl]-N-isobutylamide (19), 25) 1-(3,4-methylenedioxyphenyl)-(1E)-tetradecene (20), 18) using different chromatographic techniques. The toxicities of 8-11, 14-17 and 19 were determined against fourth instar larvae of Aedes aegypti by WHO method 26) and were found ...…”

A review of the literature and latest advances in research ofPiper sarmentosum

“…The chemical constituents identified in the plant are pellitorine (Likhitwitayawuid & Ruangrungsi, 1987;Thitima et al, 2004;Tuntiwachwuttikul et al, 2006;Hussain et al, 2010a), guineensine (Thitima et al, 2004;Tuntiwachwuttikul et al, 2006), brachystamide B (Thitima et al, 2004;Tuntiwachwuttikul et al, 2006), sarmentine (Likhitwitayawuid & Ruangrungsi, 1987;Thitima et al, 2004;Tuntiwachwuttikul et al, 2006;Hussain et al, 2010a), brachyamide B (Thitima et al, 2004), 1-piperettyl pyrrolidine (Thitima et al, 2004), 3,4,5-trimethoxycinnamoyl pyrrolidine (Thitima et al, 2004), sarmentosine (Likhitwitayawuid & Ruangrungsi, 1987;Thitima et al, 2004;Tuntiwachwuttikul et al, 2006;Hussain et al, 2010a), (+) asarinin (Thitima et al, 2004), sesamin (Thitima et al, 2004;Tuntiwachwuttikul et al, 2006), N-[9-(3,4-methylenedioxyphenyl)-2E,4E,8E-nonatrienoyl] pyrrolidine (Tuntiwachwuttikul et al, 2006), methyl piperate (Thitima et al, 2004), β-sitosterol (Likhitwitayawuid & Ruangrungsi, 1987;Thitima et al, 2004;Tuntiwachwuttikul et al, 2006;Niamsa & Chantrapromma, 1983), stigmasterol (Thitima et al, 2004), aromatic alkene (Tuntiwachwuttikul et al, 2006), 1-allyl-2-methoxy-4,5-metylenedioxybenzene (Tuntiwachwuttikul et al, 2006;Masuda et al, 1991), sarmentide C (Tuntiwachwuttikul et al, 2006), pyrrole amide (Tuntiwachwuttikul et al, ...…”