“…Execution of coordination polymers (CPs) with novel designs have grabbed comprehensive attention owing to their captivating topological architectures, in addition to their potential applications in different disciplines of catalysis, gas filtration/separation, , luminescence, drug delivery, and so forth. Due to their applications in diverse areas of research, a massive number of CPs have been synthesized. − However, it is quite a challenge for crystal engineers to rationally fabricate new CPs with desired characteristic features which are strongly influenced by some synthetic factors like temperature, nature of solvent, pH value, etc., and even by the type of building block units such as ligands, cations, and some potential template moieties. − More importantly, the ligand is the key building block concerned with the design of new CPs, according to study of a great number of ligands with distinct properties and structures, which have been reported in the past few years. In view of searching for a suitable ligand, to tune the structure, property, and functionality of CPs, ample publications have been explored regarding the utility of organic ligand with its flexibility, length, and type of substituent; however, systematic tuning of the CPs with positional isomeric effect toward structural variations remains greatly unknown. − Moreover, a little work has been reported on the positional isomeric effect, which can demonstrate the investigation of the important factors of positional isomeric ligands for controlling structural differences.…”