Structural comparison, physicochemical properties, and in vitro release profile of curcumin-loaded lyotropic liquid crystalline nanoparticle: Influence of hydrotrope as interface stabilizers

Souza, Juliana Ferreira de; Pontes, Katiusca da Silva; Alves, Thaís Francine Ribeiro; Barros, Cecília Torqueti de; Amaral, Venâncio Alves; Crescencio, Kessi; Rios, Alessandra Cândida; Batain, Fernando; Souto, Eliana B.; Severino, Patrícia; Komatsu, Daniel; Hausen, Moema de Alencar; Chaud, Marco V.

doi:10.1016/j.molliq.2020.112861

Cited by 19 publications

(8 citation statements)

References 60 publications

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“…On the other hand, the degradation rate of the skin scaffold should be proportional to the healing rate of the wounded skin [97]. Incorporation of nanobiomaterials can affect the physicochemical properties of the scaffolds and therefore their degradation rate and release profile [98]. Other important factors that can directly affect these two parameters are cross-linkers and crosslinking procedures.…”

Section: Degradation Rate and Release Profilementioning

confidence: 99%

Nanocomposite scaffolds for accelerating chronic wound healing by enhancing angiogenesis

et al. 2021

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Skin is the body’s first barrier against external pathogens that maintains the homeostasis of the body. Any serious damage to the skin could have an impact on human health and quality of life. Tissue engineering aims to improve the quality of damaged tissue regeneration. One of the most effective treatments for skin tissue regeneration is to improve angiogenesis during the healing period. Over the last decade, there has been an impressive growth of new potential applications for nanobiomaterials in tissue engineering. Various approaches have been developed to improve the rate and quality of the healing process using angiogenic nanomaterials. In this review, we focused on molecular mechanisms and key factors in angiogenesis, the role of nanobiomaterials in angiogenesis, and scaffold-based tissue engineering approaches for accelerated wound healing based on improved angiogenesis.

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Section: Degradation Rate and Release Profilementioning

confidence: 99%

Nanocomposite scaffolds for accelerating chronic wound healing by enhancing angiogenesis

et al. 2021

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“…68 In another work, the influence of P407 and sodium lauryl sulfate stabilizers function of hydrotrope type have been investigated, and a better selforganization of the mesophase was observed in comparison to the formulation without hydrotropes. 69 However, controlling the particle size and size distribution together with probable residues of solvent in the final product is more challenging for this method. 70 The existence of hydrotrope in the final formulation may also cause in vivo problems, e.g., irritation and toxicity.…”

Section: Cubosomes and Hexosomesmentioning

confidence: 99%

Cubosomes and Hexosomes as Novel Nanocarriers for Bioactive Compounds

Tan

Hosseini

Jafari

2022

J. Agric. Food Chem.

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Cubosomes and hexosomes are nanostructured liquid crystalline particles, known as biocompatible nanocarriers for drug delivery. In recent years, there has been good interest in using cubosomes and hexosomes for the delivery of bioactive compounds in functional foods. These systems feature thermodynamic stability, encapsulate both hydrophobic and hydrophilic substances, and have a high tolerance to environmental stresses and potential for controlled release. This review outlines the recent advances in cubosomes and hexosomes in the food industry, focusing on their structure, composition, formation mechanisms, and factors influencing phase transformation between cubosomes and hexosomes. The potential applications especially for the bioactive delivery are presented. The integration of cubosomes and hexosomes with other emerging encapsulation technologies such as surface coating, gelation, and incorporation of polymers are also discussed.

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“…Liquid crystals are among the most relevant pharmaceutical innovation design to enhanced water solubility, efficacy, stability, and safety of active AcI. Self-assembly nanostructure systems such as lyotropic liquid crystal have properties unique due to the structural ordering or as complex 3D-network forming lamellas, whose thermodynamic properties allow biological activity at the molecular level [69]. Liquid crystal enhancing tissue penetration of the active AcI and increase bioadhesion to the leaf, increasing efficiency and decreasing the environmental damage.…”

Section: Lipid-based Nanopesticidesmentioning

confidence: 99%

Nanopesticides in Agriculture: Benefits and Challenge in Agricultural Productivity, Toxicological Risks to Human Health and Environment

Chaud

Souto

Zielińska

et al. 2021

Toxics

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151

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Nanopesticides are nanostructures with two to three dimensions between 1 to 200 nm, used to carry agrochemical ingredients (AcI). Because of their unique properties, the loading of AcI into nanoparticles offers benefits when compared to free pesticides. However, with the fast development of new engineered nanoparticles for pests’ control, a new type of environmental waste is being produced. This paper describes the nanopesticides sources, the harmful environmental and health effects arising from pesticide exposure. The potential ameliorative impact of nanoparticles on agricultural productivity and ecosystem challenges are extensively discussed. Strategies for controlled release and stimuli-responsive systems for slow, sustained, and targeted AcI and genetic material delivery are reported. Special attention to different nanoparticles source, the environmental behavior of nanopesticides in the crop setting, and the most recent advancements and nanopesticides representative research from experimental results are revised. This review also addresses some issues and concerns in developing, formulating and toxicity pesticide products for environmentally friendly and sustainable agriculture.

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Structural comparison, physicochemical properties, and in vitro release profile of curcumin-loaded lyotropic liquid crystalline nanoparticle: Influence of hydrotrope as interface stabilizers

Cited by 19 publications

References 60 publications

Nanocomposite scaffolds for accelerating chronic wound healing by enhancing angiogenesis

Nanocomposite scaffolds for accelerating chronic wound healing by enhancing angiogenesis

Cubosomes and Hexosomes as Novel Nanocarriers for Bioactive Compounds

Nanopesticides in Agriculture: Benefits and Challenge in Agricultural Productivity, Toxicological Risks to Human Health and Environment

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