Structural characterisation and bioconjugation of an active ester containing oxorhenium(V) complex incorporating a thioether donor

Glaser, Matthias; Howard, Mark J.; Howland, Kevin; Powell, Annie K.; Rae, Michael T.; Wočadlo, Sigrid; Williamson, Richard A.; Blower, Philip J.

doi:10.1039/a804717k

Cited by 14 publications

(12 citation statements)

References 24 publications

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“…Of particular significance is, therefore, the question of the relationship between the structure and chemical composition of an ionic liquid and its melting point. 14,15 In most cases, an increasing size of the anion with the same charge leads to a further decrease in the melting point. [14][15][16][17] In general, it can be concluded that the density of comparable ionic liquids decreases as the bulkiness of the organic cation increases.…”

Section: Resultsmentioning

confidence: 99%

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Spectroscopic and Thermal-Gravimetric Investigation of two New Rhenium (V) Ionic Liquid Complexes

Alhokbany

Mahfouz

2010

Journal of Chemical Research

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Rhenium (V) ionic liquids of formula [BzEt 3 N][ReOCl 3 (MBT)(tri)] and [Et3 N][ReOCl 3 (amino)] (BzEt 3 N= benzyltriethylammonuim, Et 3 N=triethylammonium, MBT=mercaptobenzothiazole, Tri=1, 2, 4-triazole and amino= amino thiazole) were synthesised by reaction between [BzEt 3 N][ReOCl 4 ] and [Et 3 N][ReOCl 4 ] precursors and free ligands , in the presence of triethylamine. These ionic liquid complexes have been characterised by elemental analysis, spectroscopy (IR, 1H-13 C NMR, MS) and thermogravimetric studies. Geometry optimisation of [Et 3 N][ReOCl 3 (amino)] has been carried out using DFT and the predicted IR spectrum of the geometrically-optimised structure shows good agreement with experimental values.

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Section: Resultsmentioning

confidence: 99%

“…14,15 In most cases, an increasing size of the anion with the same charge leads to a further decrease in the melting point. [14][15][16][17] In general, it can be concluded that the density of comparable ionic liquids decreases as the bulkiness of the organic cation increases. 18,19 The GAUSSIAN 98 program was used in the calculations.…”

Section: Resultsmentioning

confidence: 99%

Spectroscopic and Thermal-Gravimetric Investigation of two New Rhenium (V) Ionic Liquid Complexes

Alhokbany

Mahfouz

2010

Journal of Chemical Research

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“…2,3 This procedure appeared to be unnecessarily lengthy, given that 2,3,5,6- tetrafluorophenol may be directly coupled to other carboxylic acids using 1,3-dicyclohexylcarbodiimide (DCC). 5 This note reports a simple synthesis of 2,3,5,6-tetrafluorophenyl 2-(2-nitroimidazol-1-yl) acetate (I) from 2-(2-nitroimidazol-1-yl) acetic acid (II) and commercially available 2,3,5,6-tetrafluorophenol (Scheme 1)…”

Section: Introduction and Discussionmentioning

confidence: 99%

A simplified synthesis of 2,3,5,6‐tetrafluorophenyl 2‐(2‐nitroimidazol‐1‐yl) acetate

Wilson

2003

Labelled Comp Radiopharmac

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“…There is an extensive literature, which is beyond the scope of this article, describing Tc(V) mono-oxo-complexes with linear tetradentate chelators containing a combination of sulfur and nitrogen ligands: N4 (24, 25), SN3 ( 5 , Fig. 2), and S2N2 (where S is thiolate or thioether (26) and N is an uncharged amine or a deprotonated amine or amide) (27). In addition, the Tc(V)-oxo-bis(dithiolate) core, best known in the form of the dimercaptosuccinic acid complex ( 6 , Fig.…”

Section: Technetium-99m: Small Complexesmentioning

confidence: 99%

Opportunities and Challenges for Metal Chemistry in Molecular Imaging

Southworth

Rosales

Meszaros

et al. 2016

Advances in Inorganic Chemistry

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The development of medical imaging is a highly multidisciplinary endeavor requiring the close cooperation of clinicians, physicists, engineers, biologists and chemists to identify capabilities, conceive challenges and solutions and apply them in the clinic. The chemistry described in this article illustrates how synergistic advances in these areas drive the technology and its applications forward, with each discipline producing innovations that in turn drive innovations in the others. The main thread running through the article is the shift from single photon radionuclide imaging towards PET, and in turn the emerging shift from PET/CT towards PET/MRI and further, combination of these with optical imaging. Chemistry to support these transitions is exemplified by building on a summary of the status quo, and recent developments, in technetium-99m chemistry for SPECT imaging, followed by a report of recent developments to support clinical application of short lived (Ga-68) and long-lived (Zr-89) positron emitting isotopes, copper isotopes for PET imaging, and combined modality imaging agents based on radiolabelled iron oxide based nanoparticles.

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Structural characterisation and bioconjugation of an active ester containing oxorhenium(V) complex incorporating a thioether donor

Cited by 14 publications

References 24 publications

Spectroscopic and Thermal-Gravimetric Investigation of two New Rhenium (V) Ionic Liquid Complexes

Spectroscopic and Thermal-Gravimetric Investigation of two New Rhenium (V) Ionic Liquid Complexes

A simplified synthesis of 2,3,5,6‐tetrafluorophenyl 2‐(2‐nitroimidazol‐1‐yl) acetate

Opportunities and Challenges for Metal Chemistry in Molecular Imaging

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