Structural and Conformational Studies of (Ile7) and (Leu7)Surfactins from Bacillus subtilis natto.

Itokawa, Hideji; Miyashita, T.; Morita, Hiroshi; Takeya, Koichi; Hirano, Toshihiko; Homma, Masato; Oka, Kitaro

doi:10.1248/cpb.42.604

Cited by 86 publications

(55 citation statements)

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“…It is an attractive natural compound showing a broad spectrum of antimicrobial [2,10,15] and antiviral [16][17][18][19] activities. Therefore, it is of great medical and biotechnological interest.…”

Section: Discussionmentioning

confidence: 99%

“…For example, it shows potent antimicrobial [2,10,15], antiviral [16][17][18][19], antitumor [20], and hypocholesterolemic [21] activities which are of high relevance in health care and biotechnology. As a membrane-active agent it lyses bacterial spheroplasts and protoplasts [10] as well as mycoplasma and viral membrane envelopes [15,18].…”

Section: Accepted M Manuscriptmentioning

confidence: 99%

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Physicochemical studies of the interaction of the lipoheptapeptide surfactin with lipid bilayers of l-α-dimyristoyl phosphatidylcholine

Kell

Holzwarth

Boettcher

et al. 2007

Biophysical Chemistry

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ochemical studies of the interaction of the lipoheptapeptide surfactin with lipid bilayers of L-α-dimyristoyl phosphatidylcholine. Biophysical Chemistry, Elsevier, 2007, 128 (2-3) This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. A C C E P T E D

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Section: Discussionmentioning

confidence: 99%

Section: Accepted M Manuscriptmentioning

confidence: 99%

Physicochemical studies of the interaction of the lipoheptapeptide surfactin with lipid bilayers of l-α-dimyristoyl phosphatidylcholine

Kell

Holzwarth

Boettcher

et al. 2007

Biophysical Chemistry

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“…Recently, Grangemard et al (13) acid component (5-7) as well as (b) substitutions of the isolated and characterized [ Ile4, Ile7]-and [ Ile2, Ile4, amino acid components of the peptide ring (8)(9)(10)(11)(12)(13). These Ile7]-surfactin, which were formed by supplementation of variations, rather than being genetically determined, depend L-isoleucine to the culture medium.…”

mentioning

confidence: 99%

Separation and Characterization of Surfactin Isoforms Produced byBacillus subtilisOKB 105

Kowall

Vater

Kluge

et al. 1998

Journal of Colloid and Interface Science

201

168

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“…which has been isolated are reported having high antibacterial activity against fouling bacteria (Burgess et al 2003). Bacillus pumilus sponge symbiontsIrcinia sp., produces surfactin, acyldepsipeptide (ADEP), bacircine 2, 3, 4, 5, and 5A (Itokawa et al 1994). Related research also conducted by Susilowati et al (2015) which has isolated brown algae bacteria symbionts that are B. subtilis and it has an ability to obstruct pathogenic bacteria like MRSA and Staphylococcus epidermidis.…”

Section: Identity Of Endophyte Bacteria Based On 16srrna Encoding Genementioning

confidence: 99%

Short Communication: Fish fauna of Lake Lauik Tawar and Lake Laulo, Simeulue Island, Indonesia

Muchlisin¹,

Nurfadillah²,

Arisa³

et al. 2017

Biodiversitas

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Abstract. Fitri DS, Pangastuti A, Susilowati A, Sutarno. 2017. Endophytic bacteria producing antibacterial against methicillin-resistant Staphylococcus aureus (MRSA) in seagrass from Rote Ndao, East Nusa Tenggara,. Methicillinresistant Staphylococcus aureus (MRSA) are bacteria that resistant to the various type of antibiotics and yet cannot be handled comprehensively. The discovery of new antibiotic from endophytic bacteria in seagrass of Rote Island is an option to overcome the resistance. The aims of this research were to screen endophytic bacteria inhibit MRSA from seagrass, to determine the species of the endophytic bacteria and the genetic relationship. Isolation of endophytic bacteria has carried out by inoculating surface sterilization seagrass leaves on Marine Agar (MA) medium. Selection of potential endophytic bacteria-producing anti-MRSA has done using overlay method against MRSA, gram-positive Bacillus subtilis, and gram-negative Escherichia coli. Identification of the endophytic bacteria based on the sequence of 16S rRNA encoding gene. The results showed that there were eight isolates of endophytic bacteria which have antibacterial activity against MRSA of seagrass Enhalus acoroides, Thalassia hemprichii, and Cymodocea rotundata in the Litianak and Oeseli Beaches, Rote Ndao. The diameter of inhibition zone was between 0.65-18.27 mm with narrow spectrum with broad spectrum antibacterial activity. The eight potential endophytic bacteria identity were Bacillaceae E2M1, Bacillaceae E2M3, Bacillus E2M4, Bacillus E2M7, Bacillaceae E2M8, Pseudomonadaceae C1M7, Shewanellaceae C2M3, and Rhodobacteraceae T1M3. Most of the isolates can be said to be a new species as the percent similarity of 16S rRNA gene sequence was less than 95% and promising to produce new antibacterial compounds. Phylogenetic relationship showed some isolates clustering in different groups that present the diverse groups of endophytic bacteria were found.

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Structural and Conformational Studies of (Ile7) and (Leu7)Surfactins from Bacillus subtilis natto.

Cited by 86 publications

References 0 publications

Physicochemical studies of the interaction of the lipoheptapeptide surfactin with lipid bilayers of l-α-dimyristoyl phosphatidylcholine

Physicochemical studies of the interaction of the lipoheptapeptide surfactin with lipid bilayers of l-α-dimyristoyl phosphatidylcholine

Separation and Characterization of Surfactin Isoforms Produced byBacillus subtilisOKB 105

Short Communication: Fish fauna of Lake Lauik Tawar and Lake Laulo, Simeulue Island, Indonesia

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