Structural Analysis of a Bioactive Polysaccharide, PISP1, from the Medicinal Mushroom<i>Phellinus igniarius</i>

Yang, Yan; Ye, Libin; Zhang, Jingsong; Liu, Yanfang; Tang, Qingjiu

doi:10.1271/bbb.80546

Cited by 34 publications

(15 citation statements)

References 22 publications

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“…Phellinus baumii Pilát belonging to Basidiomycota, Hymenomycetes, Aphyllophorales, Hymenochaetaceae and Phellinus, is a perennial, yellowish brown rare medicinal fungus [1]. The studies have shown that the Phellinus fruiting body has anti-tumor, immune-enhancing, hypoglycemic, antioxidant, anti-mutagenic, anti-mutation and other pharmacological effects [2][3][4]. Polysaccharide is one of the main active components of Phellinus.…”

Section: Introductionmentioning

confidence: 99%

Effects of Grinding Methods on Physicochemical Properties of Crude Polysaccharides from Phellinus baumii

Yang

Chen

et al. 2019

E3S Web Conf.

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The physicochemical properties of Phellinus baumii polysaccharides extracted from the fruiting bodies by different grinding methods were studied in this paper. Compared with ordinary grinding methods, superfine grinding technology exerts significantly higher yields of crude polysaccharides, polysaccharide contents and β-Glucan contents of six samples. HPSEC-MALLS- RI analysis shows the molecular weight distribution of P.baummii crude polysaccharides, which indicates superfine grinding technique generates higher molecular weight fractions and larger polydispersities. The 6 kinds of crude polysaccharides have obvious effects on NO generation of RAW264.7 cells, which indicated that crude polysaccharides from P.baumii may have some immune-enhancing effects. Meanwhile, CW30 and FP30 show the best immune enhancing effects. However, CW50 and CW70 exert weaker immune-enhancing effects compared with FP50 and FP70.

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Section: Introductionmentioning

confidence: 99%

Effects of Grinding Methods on Physicochemical Properties of Crude Polysaccharides from Phellinus baumii

Yang

Chen

et al. 2019

E3S Web Conf.

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“…Over the past several decades, researches have shown that the extract from the fruit body of P. igniarius has anti-inflammatory, antioxidative activities and also has the ability to be an anti-tumor [10][11][12]. However, there are few reports focusing on the relationship between the anti-tumor and immunostimulatory activities of the endo-polysaccharide extracted from the submerged fermentation product of P. igniarius (PIE).…”

Section: Introductionmentioning

confidence: 99%

Endo-polysaccharide of Phellinus igniarius exhibited anti-tumor effect through enhancement of cell mediated immunity

Chen

Pan

Li³

et al. 2011

International Immunopharmacology

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“…Numerous studies have demonstrated that the genus Phellinus (Hymenochaetaceae) is a rich source of biologically active compounds. Extracts of P. igniarius have cytotoxic, immunostimulating and anti-inflammatory activities, which are due to the presence of polysaccharide and terpene compounds [1][2][3]. P. pini is a potential source of anti-inflammatory compounds.…”

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confidence: 99%

Physiologically Active Compounds in Four Species of Phellinus

Sułkowska-Ziaja

Maślanka

Szewczyk

et al. 2017

Natural Product Communications

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The content of two groups of compounds with biological activity (non-hallucinogenic indole compounds and free phenolic acids) were analyzed in extracts of fruiting bodies of four species of Phellinus: P. igniarius, P. pini, P. pomaceus and P. robustus. The presence of indole compounds in methanolic extracts was analyzed by high-performance liquid chromatography and thin-layer chromatography coupled with densitometric detection. Three metabolites (serotonin, tryptamine, and L-tryptophan) were identified. The contents of individual indole compounds ranged from 1.70 (tryptamine in P. robustus) to 8.32 mg  100 g-1 dry weight (L-tryptophan in P. robustus). Four free phenolic acids were detected in methanolic extracts by the HPLC method. The total content ranged from 9.9 mg  100 g-1 DW (P. igniarius) to 32.5 mg  100 g-1 DW (P. robustus).

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Structural Analysis of a Bioactive Polysaccharide, PISP1, from the Medicinal MushroomPhellinus igniarius

Cited by 34 publications

References 22 publications

Effects of Grinding Methods on Physicochemical Properties of Crude Polysaccharides from Phellinus baumii

Effects of Grinding Methods on Physicochemical Properties of Crude Polysaccharides from Phellinus baumii

Endo-polysaccharide of Phellinus igniarius exhibited anti-tumor effect through enhancement of cell mediated immunity

Physiologically Active Compounds in Four Species of Phellinus

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