Abstract:Osteoarthritis (OA) mainly occurs in the elderly population and seriously affects their quality of life. The strontium (Sr) ion has shown positive effects on the bone tissue and promises on OA treatment. However, the adequate treatment dosage and the underlying mechanisms are unclear. This study investigated the effect of different concentrations of Sr ion on a mouse model of OA induced by destabilization of the medial meniscus (DMM) surgery, as well as the underlying mechanisms. DMM-induced OA mice were recei… Show more
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